Brenda Diergaarde
Overview
Explore the profile of Brenda Diergaarde including associated specialties, affiliations and a list of published articles.
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Articles
87
Citations
1617
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Recent Articles
1.
Lam A, Hueniken K, Pienkowski M, Lee J, Dong M, Diergaarde B, et al.
JAMA Otolaryngol Head Neck Surg
. 2025 Feb;
PMID: 39976935
Importance: Cigarette smoking is a strong risk factor for mortality in patients diagnosed with head and neck squamous cell carcinoma (HNSCC). However, little evidence supports which smoking metric best models...
2.
Diergaarde B, Young G, Hall D, Mazloom A, Costa G, Subramaniam S, et al.
J Surg Oncol
. 2025 Jan;
PMID: 39865324
Background And Objectives: Identification of colorectal cancer (CRC) patients at high risk of recurrence could be of substantial clinical use. We evaluated the association of ctDNA status, using a tumor-informed...
3.
Westermann L, Diergaarde B, Heidegger S, Poeck H, Szczepanski M, Reichert T, et al.
Clin Transl Oncol
. 2025 Jan;
PMID: 39776398
Background: Small extracellular vesicles (sEV) released by tumor cells (tumor-derived sEV; TEX) mediate intercellular communication between tumor and non-malignant cells and were shown to impact disease progression. This study investigates...
4.
Borhani A, Zhang P, Diergaarde B, Darwiche S, Chuperlovska K, Wang S, et al.
Abdom Radiol (NY)
. 2024 Nov;
PMID: 39487920
Background: Imaging biomarkers are emerging as non-invasive predictors of cancer prognosis and clinical outcome. We assessed tumor-specific ("radiomics") and body composition imaging features ("morphomics") extracted from baseline pre-treatment CT for...
5.
Zandberg D, Hong C, Swartz A, Hsieh R, Anderson J, Ferris R, et al.
BJC Rep
. 2024 Sep;
2(1):70.
PMID: 39281316
Background: Biomarkers that effectively predict response to anti-PD-1 mAb therapy in cancer patients are an unmet need. We evaluated the utility of small extracellular vesicles (sEV) as biomarkers of response...
6.
Thakral A, Lee J, Hou T, Hueniken K, Dudding T, Gormley M, et al.
Nat Commun
. 2024 Sep;
15(1):7835.
PMID: 39244563
HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of...
7.
Kochetov B, Bell P, Garcia P, Shalaby A, Raphael R, Raymond B, et al.
Commun Biol
. 2024 Aug;
7(1):1062.
PMID: 39215205
Multiplexed imaging technologies have made it possible to interrogate complex tissue microenvironments at sub-cellular resolution within their native spatial context. However, proper quantification of this complexity requires the ability to...
8.
Hong C, Diergaarde B, Whiteside T
BJC Rep
. 2024 Jun;
2(1).
PMID: 38938748
Background: Small (30-150nm) extracellular vesicles (sEV), also known as exosomes, play a key role in cell-to-cell signaling. They are produced by all cells, circulate freely and are present in all...
9.
Karloski E, Dudley B, Diergaarde B, Blanco A, Everett J, Levinson E, et al.
Cancer
. 2024 May;
130(19):3297-3304.
PMID: 38809542
Background: Pancreatic ductal adenocarcinoma (PDAC) surveillance is recommended for some individuals with a pathogenic or likely pathogenic variant (PV/LPV) in a PDAC susceptibility gene; the recommendation is often dependent on...
10.
Warkentin M, Al-Sawaihey H, Lam S, Liu G, Diergaarde B, Yuan J, et al.
Thorax
. 2024 Jan;
79(4):307-315.
PMID: 38195644
Background: Low-dose CT screening can reduce lung cancer-related mortality. However, most screen-detected pulmonary abnormalities do not develop into cancer and it often remains challenging to identify malignant nodules, particularly among...