Bram Slutter
Overview
Explore the profile of Bram Slutter including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
1979
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0
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Recent Articles
1.
Parma L, Sachs N, Sobczak N, Li Z, Merchant K, Pauli J, et al.
Circulation
. 2025 Feb;
151(8):581-584.
PMID: 39993040
No abstract available.
2.
Ostroumov D, Benne N, Lozano Vigario F, Escalona-Rayo O, Dodz K, Sauer S, et al.
Cell Mol Immunol
. 2024 Dec;
22(2):150-160.
PMID: 39741195
The clinical use of cancer vaccines is hampered by the low magnitude of induced T-cell responses and the need for repetitive antigen stimulation. Here, we demonstrate that liposomal formulations with...
3.
Janez S, Guzelj S, Kocbek P, de Vlieger E, Slutter B, Jakopin Z
J Med Chem
. 2024 Sep;
67(19):17585-17607.
PMID: 39344184
Herein we report on the design, synthesis and biological evaluation of a series of nucleotide-binding oligomerization-domain-containing protein 2 (NOD2) desmuramylpeptide agonists. The structural prerequisites that shape both physicochemical and immunomodulatory...
4.
5.
Ge X, Slutter B, Lambooij J, Zhou E, Ying Z, Agirman C, et al.
iScience
. 2024 May;
27(6):109830.
PMID: 38770137
The liver X receptor (LXR) is considered a therapeutic target for atherosclerosis treatment, but synthetic LXR agonists generally also cause hepatic steatosis and hypertriglyceridemia. Desmosterol, a final intermediate in cholesterol...
6.
Coban B, Wang Z, Liao C, Beslmuller K, Timmermans M, Martens J, et al.
iScience
. 2024 May;
27(5):109738.
PMID: 38706844
Tumor tissues often contain high extracellular adenosine, promoting an immunosuppressed environment linked to mesenchymal transition and immune evasion. Here, we show that loss of the epithelial transcription factor, GRHL2, triggers...
7.
Depuydt M, Schaftenaar F, Prange K, Boltjes A, Hemme E, Delfos L, et al.
Nat Cardiovasc Res
. 2024 Apr;
2(2):112-125.
PMID: 38665903
Atherosclerosis is a lipid-driven chronic inflammatory disease; however, whether it can be classified as an autoimmune disease remains unclear. In this study, we applied single-cell T cell receptor seqencing (scTCR-seq)...
8.
Schaftenaar F, van Dam A, de Bruin G, Depuydt M, de Mol J, Amersfoort J, et al.
Arterioscler Thromb Vasc Biol
. 2024 Apr;
44(6):1346-1364.
PMID: 38660806
Background: Atherosclerosis is the major underlying pathology of cardiovascular disease and is driven by dyslipidemia and inflammation. Inhibition of the immunoproteasome, a proteasome variant that is predominantly expressed by immune...
9.
de Jong M, Depuydt M, Schaftenaar F, Liu K, Maters D, Wezel A, et al.
Arterioscler Thromb Vasc Biol
. 2024 Apr;
44(6):1318-1329.
PMID: 38634281
Background: Tissue resident memory T (T) cells are a T-cell subset that resides at the site of prior antigen recognition to protect the body against reoccurring encounters. Besides their protective...
10.
Mulholland M, Depuydt M, Jakobsson G, Ljungcrantz I, Grentzmann A, To F, et al.
Cardiovasc Res
. 2024 Apr;
120(6):581-595.
PMID: 38563353
Aims: The interleukin-1 receptor accessory protein (IL1RAP) is a co-receptor required for signalling through the IL-1, IL-33, and IL-36 receptors. Using a novel anti-IL1RAP-blocking antibody, we investigated the role of...