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Bradley S Miller

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Articles 114
Citations 1338
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Recent Articles
11.
Klein K, Miller B, Mauras N
Horm Res Paediatr . 2024 Apr; :1-10. PMID: 38684152
Introduction: Phase 3 trial of 6-month subcutaneous leuprolide acetate (SC-LA) in children with central precocious puberty (CPP) demonstrated efficacy and safety. The aims of this secondary analysis were to evaluate...
12.
Miller B, Kelepouris N, Tenenbaum H, Di Carlo S, Backeljauw P
Growth Horm IGF Res . 2024 Apr; 76:101592. PMID: 38640825
Childhood growth hormone deficiency (GHD) is a rare disorder associated with significant burden on both patients and caregivers. Although previous reports have detailed aspects of the burden experienced by patients...
13.
Alter C, Boguszewski M, Clemmons D, Dobri G, Geffner M, Kelepouris N, et al.
Growth Horm IGF Res . 2024 Feb; 74:101573. PMID: 38368660
Objective: Children with growth hormone deficiency (GHD) face multiple challenges that can negatively impact the transition from pediatric to adult endocrinology care. For children with GHD resulting from brain cancer...
14.
Miller B, Blair J, Horikawa R, Linglart A, Yuen K
Drug Des Devel Ther . 2024 Feb; 18:291-306. PMID: 38333899
Growth hormone (GH) replacement therapy for growth hormone deficiency (GHD) in children and adults has for over 25 years, until recently, been administered as daily injections. This daily treatment regimen...
15.
Barbus C, Rayannavar A, Miller B, Jenkins M, Addo O, Rayes A, et al.
Am J Med Genet A . 2024 Feb; 194(7):e63554. PMID: 38317562
Patients with Fanconi anemia (FA) are often perceived to have poor growth when general population growth curves are utilized. We hypothesize that FA patients have unique growth and aimed to...
16.
Velazquez E, Miller B, Yuen K
Expert Rev Endocrinol Metab . 2023 Dec; 19(1):1-10. PMID: 38112103
Introduction: Somatrogon (NGENLA™) is a long-acting GH (LAGH) formulation that was approved in Canada in October 2021 for the treatment of pediatric growth hormone deficiency (GHD). Somatrogon has also received...
17.
Gomez R, Lamoureux R, Turner-Bowker D, Loftus J, Maghnie M, Miller B, et al.
Front Endocrinol (Lausanne) . 2023 Nov; 14:1254424. PMID: 37955005
Introduction: The standard of care for pediatric growth hormone deficiency (pGHD) is once-daily recombinant human growth hormone (rhGH). Somatrogon, a long-acting rhGH, requires less frequent, once-weekly, dosing. We describe physicians'...
18.
Kildemoes R, Backeljauw P, Hojby M, Blair J, Miller B, Mori J, et al.
J Endocr Soc . 2023 Oct; 7(11):bvad115. PMID: 37818403
Context: Growth hormone (GH) replacement therapy improves longitudinal growth and adult height in children with GH deficiency (GHD). GH stimulates insulin-like growth factor (IGF)-I release, the biomarker used for monitoring...
19.
Motorykin I, Mu J, Miller B, Li A, Clarke N, McPhaul M, et al.
Clin Chem Lab Med . 2023 Oct; 62(3):484-492. PMID: 37811857
Objectives: To determine the detection rate of IGF-1 variants in a clinical population and assess their implications. Methods: IGF-1 variants were detected based on their predicted mass-to-charge ratios. Most variants...
20.
Chen S, Bryce J, Chen M, Charmandari E, Choi J, Dou X, et al.
Horm Res Paediatr . 2023 Sep; 97(4):365-373. PMID: 37703843
Introduction: Although there are some recommendations in the literature on the assessments that should be performed in children on recombinant human growth hormone (rhGH) therapy, the level of consensus on...