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Brad E Zacharia

Explore the profile of Brad E Zacharia including associated specialties, affiliations and a list of published articles. Areas
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Articles 142
Citations 2234
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Recent Articles
1.
Tuohy K, Dowd R, Ali A, Badani A, Sichinga K, Zacharia B, et al.
Neurosurgery . 2025 Jan; PMID: 39775083
Background And Objectives: Administration of intraventricular chemotherapy through Ommaya reservoir is indicated for certain forms of leptomeningeal disease. However, ventricular reservoirs carry a substantial risk of infection. The conventional approach...
2.
Krishnamoorthy A, Bailey D, Specht C, Zacharia B
Cureus . 2024 Oct; 16(9):e70182. PMID: 39463506
A 64-year-old female presented with extensive osseous erosion of the central skull base from a large tumor, which was evaluated with a combination of CT and MRI. Susceptibility-weighted imaging (SWI)...
3.
Lu T, Yee P, Chih S, Tang M, Chen H, Aregawi D, et al.
EMBO J . 2024 May; 43(13):2582-2605. PMID: 38806658
Necrosis in solid tumors is commonly associated with poor prognostic but how these lesions expand remains unclear. Studies have found that neutrophils associate with and contribute to necrosis development in...
4.
Duzkalir A, Samanci Y, Lee C, Yang H, Niranjan A, Lunsford L, et al.
J Neurosurg . 2024 May; 141(5):1324-1331. PMID: 38728764
Objective: Accounting for approximately 15% of primary liver cancers and 3% of gastrointestinal malignancies, cholangiocarcinoma (CCA) poses a serious health concern given its high mortality rate. Managing brain metastases (BMs)...
5.
Mikolajewicz N, Yee P, Bhanja D, Trifoi M, Miller A, Metellus P, et al.
J Clin Oncol . 2024 Apr; 42(16):1961-1974. PMID: 38608213
Effective diagnosis, prognostication, and management of CNS malignancies traditionally involves invasive brain biopsies that pose significant risk to the patient. Sampling and molecular profiling of cerebrospinal fluid (CSF) is a...
6.
Miccio J, Tian Z, Mahase S, Lin C, Choi S, Zacharia B, et al.
Commun Med (Lond) . 2024 Feb; 4(1):27. PMID: 38388667
Background: Brain metastases (BM) affect clinical management and prognosis but limited resources exist to estimate BM risk in newly diagnosed cancer patients. Additionally, guidelines for brain MRI screening are limited....
7.
Bailey D, John K, Daggubati L, Zacharia B
Cureus . 2024 Feb; 16(1):e52479. PMID: 38371126
In this case report, we discuss a patient who experienced spontaneous regression of multiple intracranial meningiomas that were treated conservatively for 5 years after cessation of megestrol acetate, an exogenous...
8.
Shenoy G, Slagle-Webb B, Khunsriraksakul C, Pandya Shesh B, Luo J, Khristov V, et al.
Sci Rep . 2024 Jan; 14(1):2389. PMID: 38287054
The association between anemia and outcomes in glioblastoma patients is unclear. We analyzed data from 1346 histologically confirmed adult glioblastoma patients in the TriNetX Research Network. Median hemoglobin and hematocrit...
9.
Koga S, Hodges W, Adamyan H, Hayes T, Fecci P, Tsvankin V, et al.
Front Neurol . 2024 Jan; 14:1322815. PMID: 38259649
Background: Peritumoral edema alters diffusion anisotropy, resulting in false negatives in tractography reconstructions negatively impacting surgical decision-making. With supratotal resections tied to survival benefit in glioma patients, advanced diffusion modeling...
10.
Lee I, Hanft S, Schulder M, Judy K, Wong E, Elder J, et al.
Future Oncol . 2023 Dec; 20(10):579-591. PMID: 38060340
Standard-of-care first-line therapy for patients with newly diagnosed glioblastoma (ndGBM) is maximal safe surgical resection, then concurrent radiotherapy and temozolomide, followed by maintenance temozolomide. IGV-001, the first product of the...