Boukje M Beuger
Overview
Explore the profile of Boukje M Beuger including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
145
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Recent Articles
11.
Meinderts S, Oldenborg P, Beuger B, Klei T, Johansson J, Kuijpers T, et al.
Blood Adv
. 2018 Jan;
1(14):875-886.
PMID: 29296731
Red blood cell (RBC) clearance is known to occur primarily in the spleen, and is presumed to be executed by red pulp macrophages. Erythrophagocytosis in the spleen takes place as...
12.
Straat M, Tuip A, Klei T, Beuger B, Roelofs J, van Bruggen R, et al.
Shock
. 2017 Sep;
48(4):484-489.
PMID: 28915218
Background: Red blood cell (RBC) transfusion is associated with organ failure, in particular in the critically ill. We hypothesized that endotoxemia contributes to increased trapping of RBCs in organs. Furthermore,...
13.
Klei T, Kheradmand Kia S, Veldthuis M, Beuger B, Geissler J, Dehbozorgian J, et al.
Eur J Haematol
. 2017 Mar;
98(6):584-589.
PMID: 28295642
Objective: Here, we present a 7-year-old patient suffering from severe haemolytic anaemia. The most common cause of chronic hereditary non-spherocytic haemolytic anaemia is red blood cell pyruvate kinase (PK-R) deficiency....
14.
Kostova E, Beuger B, Veldthuis M, Van Der Werff Ten Bosch J, Kuhnle I, van den Akker E, et al.
Exp Hematol
. 2015 Sep;
43(12):1072-1076.e2.
PMID: 26320718
Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is a rare genetic disorder caused by mutations in STXBP2/Munc18-2. Munc18-2 plays a role in the degranulation machinery of natural killer cells and cytotoxic...
15.
Kostova E, Beuger B, Klei T, Halonen P, Lieftink C, Beijersbergen R, et al.
Biosci Rep
. 2015 Mar;
35(2).
PMID: 25757360
Even though red blood cell (RBC) vesiculation is a well-documented phenomenon, notably in the context of RBC aging and blood transfusion, the exact signalling pathways and kinases involved in this...