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Boudewijn P F Lelieveldt

Explore the profile of Boudewijn P F Lelieveldt including associated specialties, affiliations and a list of published articles. Areas
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Articles 116
Citations 2778
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Recent Articles
1.
Abdelaal T, Grossouw L, Pasterkamp R, Lelieveldt B, Reinders M, Mahfouz A
NAR Genom Bioinform . 2024 Aug; 6(3):lqae100. PMID: 39108639
RNA Velocity allows the inference of cellular differentiation trajectories from single-cell RNA sequencing (scRNA-seq) data. It would be highly interesting to study these differentiation dynamics in the spatial context of...
2.
Neve O, Chen Y, Tao Q, Romeijn S, De Boer N, Grootjans W, et al.
Radiol Artif Intell . 2022 Aug; 4(4):e210300. PMID: 35923375
Purpose: To develop automated vestibular schwannoma measurements on contrast-enhanced T1- and T2-weighted MRI scans. Materials And Methods: MRI data from 214 patients in 37 different centers were retrospectively analyzed between...
3.
van Unen V, Ouboter L, Li N, Schreurs M, Abdelaal T, Kooy-Winkelaar Y, et al.
Front Immunol . 2022 Jul; 13:893803. PMID: 35812429
Chronic intestinal inflammation underlies inflammatory bowel disease (IBD). Previous studies indicated alterations in the cellular immune system; however, it has been challenging to interrogate the role of all immune cell...
4.
Brouwer T, de Vries N, Abdelaal T, Krog R, Li Z, Ruano D, et al.
J Immunother Cancer . 2022 Jul; 10(7). PMID: 35793870
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in need of effective (immuno)therapeutic treatment strategies. For the optimal application and development of cancer immunotherapies, a comprehensive understanding of...
5.
Zhou Z, Zu X, Wang Y, Lelieveldt B, Tao Q
IEEE Trans Vis Comput Graph . 2021 Oct; 28(2):1237-1248. PMID: 34699363
Embedding high-dimensional data onto a low-dimensional manifold is of both theoretical and practical value. In this article, we propose to combine deep neural networks (DNN) with mathematics-guided embedding rules for...
6.
Koolstra K, Bornert P, Lelieveldt B, Webb A, Dzyubachyk O
MAGMA . 2021 Oct; 35(2):223-234. PMID: 34687369
Objective: To visualize the encoding capability of magnetic resonance fingerprinting (MRF) dictionaries. Materials And Methods: High-dimensional MRF dictionaries were simulated and embedded into a lower-dimensional space using t-distributed stochastic neighbor...
7.
Ijsselsteijn M, Somarakis A, Lelieveldt B, Hollt T, de Miranda N
Cytometry A . 2021 Jul; 99(12):1187-1197. PMID: 34196108
Imaging mass cytometry (IMC) allows the detection of multiple antigens (approximately 40 markers) combined with spatial information, making it a unique tool for the evaluation of complex biological systems. Due...
8.
de Jong S, van Unen V, Manurung M, Stam K, Goeman J, Jochems S, et al.
Nat Immunol . 2021 Apr; 22(5):654-665. PMID: 33888898
Controlled human infections provide opportunities to study the interaction between the immune system and malaria parasites, which is essential for vaccine development. Here, we compared immune signatures of malaria-naive Europeans...
9.
Kenkhuis B, Somarakis A, de Haan L, Dzyubachyk O, Ijsselsteijn M, de Miranda N, et al.
Acta Neuropathol Commun . 2021 Feb; 9(1):27. PMID: 33597025
Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the...
10.
Abdelaal T, de Raadt P, Lelieveldt B, Reinders M, Mahfouz A
Bioinformatics . 2020 Dec; 36(Suppl_2):i849-i856. PMID: 33381821
Motivation: Single cell data measures multiple cellular markers at the single-cell level for thousands to millions of cells. Identification of distinct cell populations is a key step for further biological...