Botond Z Igyarto
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Explore the profile of Botond Z Igyarto including associated specialties, affiliations and a list of published articles.
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39
Citations
2433
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Recent Articles
1.
Bouteau A, Qin Z, Zurawski S, Zurawski G, Igyarto B
bioRxiv
. 2025 Jan;
PMID: 39868337
Dendritic cells (DCs) are key regulators of adaptive immunity, guiding T helper (Th) cell differentiation through antigen presentation, co-stimulation, and cytokine production. However, in steady-state conditions, certain DC subsets, such...
2.
Igyarto B, Qin Z
Front Immunol
. 2024 Feb;
15:1336906.
PMID: 38390323
The mRNA-LNP vaccine has received much attention during the COVID-19 pandemic since it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries. Based on early...
3.
Herbst C, Bouteau A, Menyko E, Qin Z, Gyenge E, Su Q, et al.
iScience
. 2024 Feb;
27(3):109119.
PMID: 38384841
In a previous report, keratinocytes were shown to share their gene expression profile with surrounding Langerhans cells (LCs), influencing LC biology. Here, we investigated whether transferred material could substitute for...
4.
Herbst C, Bouteau A, Menyko E, Qin Z, Su Q, Buelvas D, et al.
bioRxiv
. 2023 Aug;
PMID: 37546718
Macrophages and dendritic cells (DCs) in peripheral tissue interact closely with their local microenvironment by scavenging protein and nucleic acids released by neighboring cells. Material transfer between cell types is...
5.
Herbst C, Harshyne L, Igyarto B
Front Immunol
. 2022 Nov;
13:1053582.
PMID: 36389660
Dendritic cells (DCs) are required for the initiation of the adaptive immune response. Their ability to acquire antigens in the periphery is a critical step in this process. DCs express...
6.
Whitley S, Li M, Kashem S, Hirai T, Igyarto B, Knizner K, et al.
Sci Immunol
. 2022 Nov;
7(77):eabq3254.
PMID: 36367947
The cytokine interleukin-23 (IL-23) is critical for development and maintenance of autoimmune inflammation in nonlymphoid tissues; however, the mechanism through which IL-23 supports tissue-specific immunity remains unclear. In mice, we...
7.
Qin Z, Bouteau A, Herbst C, Igyarto B
PLoS Pathog
. 2022 Sep;
18(9):e1010830.
PMID: 36054264
Hundreds of millions of SARS-CoV-2 mRNA-LNP vaccine doses have already been administered to humans. However, we lack a comprehensive understanding of the immune effects of this platform. The mRNA-LNP-based SARS-CoV-2...
8.
Qin Z, Bouteau A, Herbst C, Igyarto B
bioRxiv
. 2022 Aug;
PMID: 36032972
Authors Summary: We bring experimental evidence that pre-exposure to mRNA-LNPs or its LNP component affects innate and adaptive immune responses. Pre-exposure to mRNA-LNPs led to long-term inhibition of the adaptive...
9.
Igyarto B
Microorganisms
. 2022 Jul;
10(7).
PMID: 35889182
This analysis piece will attempt to examine some of the critical pandemic-related measures implemented in the United States from an immunological perspective and pinpoint caveats that should have been considered...
10.
Lin Y, Perovanovic J, Kong Y, Igyarto B, Zurawski S, Tantin D, et al.
Diabetes
. 2022 May;
71(8):1735-1745.
PMID: 35622068
Thymic presentation of self-antigens is critical for establishing a functional yet self-tolerant T-cell population. Hybrid peptides formed through transpeptidation within pancreatic β-cell lysosomes have been proposed as a new class...