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Boris Rogelj

Explore the profile of Boris Rogelj including associated specialties, affiliations and a list of published articles. Areas
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Articles 79
Citations 6590
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Recent Articles
1.
Govaerts J, Van Breedam E, De Beuckeleer S, Goethals C, DIncal C, Di Stefano J, et al.
Front Immunol . 2024 Oct; 15:1458967. PMID: 39351233
Varicella-zoster virus (VZV) encephalitis and meningitis are potential central nervous system (CNS) complications following primary VZV infection or reactivation. With Type-I interferon (IFN) signalling being an important first line cellular...
2.
Di Stefano J, Garcia-Pupo L, Di Marco F, Motaln H, Govaerts J, Van Breedam E, et al.
Brain Behav Immun . 2024 Jul; 121:1-12. PMID: 39002812
induced-pluripotent stem cell (iPSC)-derived neurospheroid (NSPH) models are an emerging in vitro toolkit to study the influence of inflammatory triggers on neurodegeneration and repair in a 3D neural environment. In...
3.
Manzoni C, Kia D, Ferrari R, Leonenko G, Costa B, Saba V, et al.
Am J Hum Genet . 2024 Jun; 111(7):1316-1329. PMID: 38889728
Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the field mainly focus on familial forms of disease (fFTDs), while studies...
4.
Cvetko M, Knific T, Frangez R, Motaln H, Rogelj B, Alibegovic A, et al.
J Forensic Sci . 2024 Mar; 69(3):1094-1101. PMID: 38491758
The aim of the present study was to investigate the effects of time, temperature, and burial in a natural environment on the viability of chondrocytes in porcine femoral condyles using...
5.
De Marchi F, Munitic I, Vidatic L, Papic E, Racki V, Nimac J, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893165
Many potential immune therapeutic targets are similarly affected in adult-onset neurodegenerative diseases, such as Alzheimer's (AD) disease, Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD), as well...
6.
Malnar crnigoj M, cercek U, Yin X, Ho M, Repic Lampret B, Neumann M, et al.
Nat Commun . 2023 Sep; 14(1):5764. PMID: 37717009
The expanded hexanucleotide GGGGCC repeat mutation in the C9orf72 gene is the main genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. Under one disease mechanism, sense and antisense transcripts...
7.
Motaln H, Rogelj B
Cells . 2023 Aug; 12(16). PMID: 37626851
Differentiated status, low regenerative capacity and complex signaling make neuronal tissues highly susceptible to translating an imbalance in cell homeostasis into cell death. The high rate of neurodegenerative diseases in...
8.
Mohovic N, Peradinovic J, Markovinovic A, Cimbro R, Minic Z, Dominovic M, et al.
Sci Rep . 2023 Jul; 13(1):11840. PMID: 37481656
Optineurin is a multifunctional polyubiquitin-binding protein implicated in inflammatory signalling. Optineurin mutations are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), neurodegenerative diseases characterised by neuronal loss, neuroinflammation,...
9.
De Marchi F, Franjkic T, Schito P, Russo T, Nimac J, Chami A, et al.
Biomedicines . 2023 Jun; 11(6). PMID: 37371694
Proteinopathy and neuroinflammation are two main hallmarks of neurodegenerative diseases. They also represent rare common events in an exceptionally broad landscape of genetic, environmental, neuropathologic, and clinical heterogeneity present in...
10.
Motaln H, cercek U, Yamoah A, Tripathi P, Aronica E, Goswami A, et al.
Brain . 2023 Apr; 146(10):4088-4104. PMID: 37071594
Nuclear to cytoplasmic mislocalization and aggregation of multiple RNA-binding proteins (RBPs), including FUS, are the main neuropathological features of the majority of cases of amyotrophic lateral sclerosis (ALS) and frontotemporal...