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Bonnie J Cuthbert

Explore the profile of Bonnie J Cuthbert including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 107
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Recent Articles
1.
Cuthbert B, Chen X, Burley K, Batot G, Contreras H, Dixon S, et al.
Microorganisms . 2025 Jan; 12(12. PMID: 39770668
(Mtb) is the causative agent of tuberculosis, the world's deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host's defenses and survive intracellularly. Mtb's oxidative stress...
2.
Jensen S, Cuthbert B, Garza-Sanchez F, Helou C, de Miranda R, Goulding C, et al.
Nat Commun . 2024 Oct; 15(1):8804. PMID: 39394186
Advanced glycation end-products (AGE) are a pervasive form of protein damage implicated in the pathogenesis of neurodegenerative disease, atherosclerosis and diabetes mellitus. Glycation is typically mediated by reactive dicarbonyl compounds...
3.
Cuthbert B, Mendoza J, de Miranda R, Papavinasasundaram K, Sassetti C, Goulding C
Metallomics . 2024 Mar; 16(3). PMID: 38425033
The tuberculosis (TB) emergency has been a pressing health threat for decades. With the emergence of drug-resistant TB and complications from the COVID-19 pandemic, the TB health crisis is more...
4.
de Miranda R, Cuthbert B, Klevorn T, Chao A, Mendoza J, Arbing M, et al.
PLoS Pathog . 2023 Sep; 19(9):e1011650. PMID: 37747938
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, poses a great threat to human health. With the emergence of drug resistant Mtb strains, new therapeutics are desperately needed. As iron...
5.
Bartelli N, Passanisi V, Michalska K, Song K, Nhan D, Zhou H, et al.
Nat Commun . 2022 Oct; 13(1):6251. PMID: 36271082
No abstract available.
6.
Bartelli N, Passanisi V, Michalska K, Song K, Nhan D, Zhou H, et al.
Nat Commun . 2022 Aug; 13(1):5078. PMID: 36038560
Many Gram-negative bacteria use CdiA effector proteins to inhibit the growth of neighboring competitors. CdiA transfers its toxic CdiA-CT region into the periplasm of target cells, where it is released...
7.
Cuthbert B, Hayes C, Goulding C
Front Mol Biosci . 2022 May; 9:866854. PMID: 35558562
Bacteria live in complex communities and environments, competing for space and nutrients. Within their niche habitats, bacteria have developed various inter-bacterial mechanisms to compete and communicate. One such mechanism is...
8.
Burley K, Cuthbert B, Basu P, Newcombe J, Irimpan E, Quechol R, et al.
ACS Infect Dis . 2020 Dec; 7(1):174-188. PMID: 33356117
Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane...
9.
Nainar S, Cuthbert B, Lim N, England W, Ke K, Sophal K, et al.
Nat Methods . 2020 Feb; 17(3):311-318. PMID: 32015544
Tissues and organs are composed of diverse cell types, which poses a major challenge for cell-type-specific profiling of gene expression. Current metabolic labeling methods rely on exogenous pyrimidine analogs that...
10.
Cuthbert B, Burley K, Goulding C
RNA Biol . 2017 Nov; 15(1):9-12. PMID: 29099294
Bovine pancreatic ribonuclease (RNase A) is the founding member of the RNase A superfamily. Members of this superfamily of ribonucleases have high sequence diversity, but possess a similar structural fold,...