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Bojan Vujkovac

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Articles 36
Citations 627
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Recent Articles
1.
Levstek T, Bahcic E, Vujkovac B, Cokan Vujkovac A, Tesovnik T, Remec Z, et al.
Cells . 2025 Feb; 14(3). PMID: 39937009
Fabry nephropathy is a life-threatening complication of Fabry disease characterized by complex and incompletely understood pathophysiological processes possibly linked to premature aging. We aimed to investigate leukocyte telomere length (LTL),...
2.
Levstek T, Breznik N, Vujkovac B, Nowak A, Trebusak Podkrajsek K
Biomedicines . 2024 Aug; 12(8). PMID: 39200189
Fabry disease (FD) leads to significant morbidity and mortality, which may indicate accelerated ageing. However, it is still unclear whether there is a relationship between telomere length (TL), a marker...
3.
Wallace E, Goker-Alpan O, Wilcox W, Holida M, Bernat J, Longo N, et al.
J Med Genet . 2023 Nov; 61(6):520-530. PMID: 37940383
Background: Pegunigalsidase alfa is a PEGylated α-galactosidase A enzyme replacement therapy. BALANCE (NCT02795676) assessed non-inferiority of pegunigalsidase alfa versus agalsidase beta in adults with Fabry disease with an annualised estimated...
4.
Linhart A, Dostalova G, Nicholls K, West M, Tondel C, Jovanovic A, et al.
Orphanet J Rare Dis . 2023 Oct; 18(1):332. PMID: 37865771
Background: Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods: BRIDGE is a phase 3 open-label,...
5.
Levstek T, Vujkovac B, Cokan Vujkovac A, Trebusak Podkrajsek K
Front Med (Lausanne) . 2023 Apr; 10:1143905. PMID: 37035314
Introduction: Early initiation is essential for successful treatment of Fabry disease, but sensitive and noninvasive biomarkers of Fabry nephropathy are lacking. Urinary extracellular vesicles (uEVs) represent a promising source of...
6.
Cybulla M, Nicholls K, Feriozzi S, Linhart A, Torras J, Vujkovac B, et al.
J Clin Med . 2022 Aug; 11(16). PMID: 36013057
Fabry disease is a rare lysosomal storage disorder caused by mutations in the GLA gene, which, without treatment, can cause significant renal dysfunction. We evaluated the effects of enzyme replacement...
7.
Germain D, Altarescu G, Barriales-Villa R, Mignani R, Pawlaczyk K, Pieruzzi F, et al.
Mol Genet Metab . 2022 Aug; 137(1-2):49-61. PMID: 35926321
Fabry disease is an X-linked inherited lysosomal disorder that causes accumulation of glycosphingolipids in body fluids and tissues, leading to progressive organ damage and reduced life expectancy. It can affect...
8.
Vujkovac B, Kirbis I, Keber T, Cokan Vujkovac A, Tretjak M, Rados Krnel S
Clin Kidney J . 2022 Feb; 15(2):269-277. PMID: 35145641
Background: Fabry disease (FD) is a rare X-linked disorder of sphingolipid metabolism that results in chronic proteinuric nephropathy. Podocytes are one of the most affected renal cells and play an...
9.
Hughes D, Aguiar P, Lidove O, Nicholls K, Nowak A, Thomas M, et al.
Orphanet J Rare Dis . 2022 Feb; 17(1):42. PMID: 35135579
Background: Variable disease progression confounds accurate prognosis in Fabry disease. Evidence supports the long-term benefit of early intervention with disease-specific therapy, but current guidelines recommend treatment initiation based on signs...
10.
Levstek T, Mlinsek T, Holcar M, Goricar K, Lenassi M, Dolzan V, et al.
Genes (Basel) . 2021 Aug; 12(7). PMID: 34356073
Current biomarkers of Fabry nephropathy lack sensitivity in detecting early kidney damage and do not predict progression of nephropathy. Urinary extracellular vesicles (uEVs) and their molecular cargo could reflect early...