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Bojan Sedmak

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Articles 12
Citations 118
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Recent Articles
1.
Bubik A, Frangez R, Zuzek M, Gutierrez-Aguirre I, Lah T, Sedmak B
Toxins (Basel) . 2024 Sep; 16(9). PMID: 39330832
The systemic toxicity of cyclic peptides produced by cyanobacteria (CCPs) is not yet completely understood. Apart from the most known damages to the liver and kidneys, symptoms of their neurotoxicity...
2.
Meglic A, Pecman A, Rozina T, Lestan D, Sedmak B
J Environ Sci (China) . 2017 Apr; 53:248-261. PMID: 28372749
Cyanobacterial blooms are global phenomena that can occur in calm and nutrient-rich (eutrophic) fresh and marine waters. Human exposure to cyanobacteria and their biologically active products is possible during water...
3.
Frangez R, Kosec M, Sedmak B, Beravs K, Demsar F, Juntes P, et al.
Pflugers Arch . 2016 Dec; 440(Suppl 1):R103-R104. PMID: 28008499
The subchronic effects of cyanobacterial lyophilizate (CL) containing microcystins on liver were investigated in female New Zealand rabbits. Sterilised CL containing microcystins was injected i.p. Liver toxicity was assessed by...
4.
Ding Y, Song L, Sedmak B
PLoS One . 2013 Sep; 8(9):e73919. PMID: 24058503
Due to the stratospheric ozone depletion, several organisms will become exposed to increased biologically active UVB (280-320 nm) radiation, not only at polar but also at temperate and tropical latitudes....
5.
Harel M, Weiss G, Daniel E, Wilenz A, Hadas O, Sukenik A, et al.
Environ Microbiol Rep . 2013 Jun; 4(3):342-9. PMID: 23760798
The reasons for the apparent dominance of the toxic cyanobacterium Microcystis sp., reflected by its massive blooms in many fresh water bodies, are poorly understood. We show that in addition...
6.
Bubik A, Sedmak B, Novinec M, Lenarcic B, Lah T
Biol Chem . 2008 Aug; 389(10):1339-46. PMID: 18713022
Toxic cyanobacterial blooms are a rich source of metabolites having a variety of biological activities. Two main groups of cyclic peptides, depsipeptides and ureido linkage-containing peptides, reportedly inhibit serine peptidases....
7.
Sedmak B, Elersek T
Microb Ecol . 2006 Apr; 51(4):508-15. PMID: 16645927
Dissolved microcystins (MCs) are regularly present in water dominated by microcystin-producing, bloom-forming cyanobacteria. In vitro experiments with environmentally feasible concentrations (5 x 10(-7) M) of the three most common microcystins,...
8.
Sedmak B, Elersek T
Microb Ecol . 2005 Oct; 50(2):298-305. PMID: 16215645
Dissolved microcystins (MC) are regularly present in water dominated by microcystin-producing, bloom-forming cyanobacteria. In vitro experiments with environmentally feasible concentrations (5 x 10(-7) M) of the three most common microcystins,...
9.
Grach-Pogrebinsky O, Sedmak B, Carmeli S
J Nat Prod . 2004 Mar; 67(3):337-42. PMID: 15043406
Two novel microcystins, seco[d-Asp(3)]microcystin-RR (1) and [d-Asp(3),d-Glu(OMe)(6)]-microcystin-RR (2), along with the known [d-Asp(3)]microcystin-RR (3), were isolated from a Planktothrix rubescens toxic bloom collected in Lake Bled, Slovenia. The structures were...
10.
Milutinovic A, Zivin M, Zorc-Pleskovic R, Sedmak B, Suput D
Toxicon . 2003 Oct; 42(3):281-8. PMID: 14559079
Acute intoxication with MC-LR induces cytoskeletal alterations, apoptosis and necrosis of hepatocytes resulting in intrahepatic hemorrhage. Preliminary results have shown that chronic treatment of rats with intraperitoneal injections of sublethal...