Boel De Paepe
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Explore the profile of Boel De Paepe including associated specialties, affiliations and a list of published articles.
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105
Citations
1468
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Recent Articles
11.
Rothwell S, Amos C, Miller F, Rider L, Lundberg I, Gregersen P, et al.
Arthritis Rheumatol
. 2022 Dec;
75(6):1021-1027.
PMID: 36580032
Objective: The idiopathic inflammatory myopathies (IIMs) are heterogeneous diseases thought to be initiated by immune activation in genetically predisposed individuals. We imputed variants from the ImmunoChip array using a large...
12.
De Paepe B
Int J Mol Sci
. 2022 Nov;
23(21).
PMID: 36361969
Growth differentiation factor 15 (GDF-15) is a stress-induced transforming growth factor-β superfamily cytokine with versatile functions in human health. Elevated GDF-15 blood levels associate with multiple pathological conditions, and are...
13.
Zhou D, King E, Rothwell S, Krystufkova O, Notarnicola A, Coss S, et al.
Ann Rheum Dis
. 2022 Sep;
82(2):235-245.
PMID: 36171069
Background: Idiopathic inflammatory myopathies (IIM) are a group of autoimmune diseases characterised by myositis-related autoantibodies plus infiltration of leucocytes into muscles and/or the skin, leading to the destruction of blood...
14.
Cosemans G, Merckx C, De Bleecker J, De Paepe B
Front Biosci (Schol Ed)
. 2022 Sep;
14(3):19.
PMID: 36137979
Background: Stress-inducible heat shock protein 70 (HSP70) is both a protective chaperone involved in protein homeostasis and an immune regulator. In both capacities, HSP70 has been implicated in muscle disorders,...
15.
Boterberg S, Vantroys E, De Paepe B, Van Coster R, Roeyers H
PLoS One
. 2022 Sep;
17(9):e0274310.
PMID: 36084111
There is increasing evidence that diseases caused by dysfunctional mitochondria (MD) are associated with autism spectrum disorder (ASD). A comprehensive meta-analysis showed that developmental regression was reported in half of...
16.
Merckx C, Zschuntzsch J, Meyer S, Raedt R, Verschuere H, Schmidt J, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36076964
Duchenne Muscular Dystrophy (DMD) is a debilitating muscle disorder that condemns patients to year-long dependency on glucocorticoids. Chronic glucocorticoid use elicits many unfavourable side-effects without offering satisfying clinical improvement, thus,...
17.
De Paepe B, Smet J, Kopajtich R, Prokisch H, Van Coster R, Vanlander A
Pediatr Res
. 2022 Jun;
93(4):740-743.
PMID: 35750896
No abstract available.
18.
Merckx C, Cosemans G, Zschuntzsch J, Raedt R, Schmidt J, De Paepe B, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328671
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration. Osmotic stress participates to DMD pathology and altered levels of osmolyte pathway members have been reported. The...
19.
Merckx C, De Paepe B
Metabolites
. 2022 Feb;
12(2).
PMID: 35208266
Taurine (2-aminoethanesulfonic acid) is required for ensuring proper muscle functioning. Knockout of the taurine transporter in mice results in low taurine concentrations in the muscle and associates with myofiber necrosis...
20.
Versluys L, Ervilha Pereira P, Schuermans N, De Paepe B, De Bleecker J, Bogaert E, et al.
Front Neurosci
. 2022 Feb;
16:815765.
PMID: 35185458
TAR DNA-binding protein 43, mostly referred to as TDP-43 (encoded by the gene) is strongly linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). From the...