Bobo Wing-Yee Mok
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Explore the profile of Bobo Wing-Yee Mok including associated specialties, affiliations and a list of published articles.
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28
Citations
932
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Recent Articles
11.
Lu L, Chu A, Zhang R, Chan W, Ip J, Tsoi H, et al.
EBioMedicine
. 2021 Aug;
71:103544.
PMID: 34419925
Background: Several SARS-CoV-2 lineages with spike receptor binding domain (RBD) N501Y mutation have spread globally. We evaluated the impact of N501Y on neutralizing activity of COVID-19 convalescent sera and on...
12.
Meng F, Siu G, Mok B, Sun J, Fung K, Lam J, et al.
Cells
. 2021 Aug;
10(7).
PMID: 34359932
MicroRNAs (miRNAs) are critical regulators of gene expression that may be used to identify the pathological pathways influenced by disease and cellular interactions. Viral miRNAs (v-miRNAs) encoded by both DNA...
13.
Liu Y, Mok B, Wang P, Kuo R, Chen H, Shih S
mBio
. 2021 Jul;
12(4):e0094521.
PMID: 34311580
Cellular 5'-3' exoribonuclease 1 (XRN1) is best known for its role as a decay factor, which by degrading 5' monophosphate RNA after the decapping of DCP2 in P-bodies (PBs) in...
14.
Liu S, Mok B, Deng S, Liu H, Wang P, Song W, et al.
Cell Rep
. 2021 Jun;
35(10):109213.
PMID: 34107256
Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing...
15.
Wang P, Lau S, Deng S, Chen P, Mok B, Zhang A, et al.
Nat Commun
. 2021 May;
12(1):2790.
PMID: 33986286
SARS-CoV-2 is of zoonotic origin and contains a PRRA polybasic cleavage motif which is considered critical for efficient infection and transmission in humans. We previously reported on a panel of...
16.
Ho J, Mok B, Campisi L, Jordan T, Yildiz S, Parameswaran S, et al.
Cell
. 2021 Apr;
184(10):2618-2632.e17.
PMID: 33836156
The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently affecting millions of lives worldwide. Large retrospective studies indicate that an elevated level of inflammatory cytokines...
17.
Ho J, Mok B, Campisi L, Jordan T, Yildiz S, Parameswaran S, et al.
bioRxiv
. 2020 Dec;
PMID: 33299999
The ongoing pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is currently affecting millions of lives worldwide. Large retrospective studies indicate that an elevated level of inflammatory cytokines...
18.
Lau S, Wang P, Mok B, Zhang A, Chu H, Lee A, et al.
Emerg Microbes Infect
. 2020 Apr;
9(1):837-842.
PMID: 32301390
The emergence of SARS-CoV-2 has led to the current global coronavirus pandemic and more than one million infections since December 2019. The exact origin of SARS-CoV-2 remains elusive, but the...
19.
Verhoeven R, Tong S, Mok B, Liu J, He S, Zong J, et al.
Front Oncol
. 2019 Nov;
9:1120.
PMID: 31696060
Epstein-Barr virus (EBV) establishes lifelong latent infection in humans and is associated with several lymphoid and epithelial cancers. In nasopharyngeal carcinoma (NPC), EBV expresses few viral proteins but elevated levels...
20.
Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines
Wang P, Zheng M, Lau S, Chen P, Mok B, Liu S, et al.
mBio
. 2019 Sep;
10(5).
PMID: 31530680
Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host immune response. Deletion of NS1 (DelNS1)...