Bobby Thomas
Overview
Explore the profile of Bobby Thomas including associated specialties, affiliations and a list of published articles.
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62
Citations
3617
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Recent Articles
1.
Soni P, Kaidery N, Sharma S, Gazaryan I, Nikulin S, Hushpulian D, et al.
Front Pharmacol
. 2024 Jul;
15:1390798.
PMID: 39040474
Neurodegenerative diseases represent a pressing global health challenge, and the identification of novel mechanisms underlying their pathogenesis is of utmost importance. Ferroptosis, a non-apoptotic form of regulated cell death characterized...
2.
Hushpulian D, Kaidery N, Dutta D, Sharma S, Gazaryan I, Thomas B
Bioessays
. 2023 Nov;
46(1):e2300176.
PMID: 37919861
The transcription factor Nrf2 is the master regulator of cellular stress response, facilitating the expression of cytoprotective genes, including those responsible for drug detoxification, immunomodulation, and iron metabolism. FDA-approved Nrf2...
3.
Ahuja M, Kaidery N, Dutta D, Attucks O, Kazakov E, Gazaryan I, et al.
Antioxidants (Basel)
. 2022 Sep;
11(9).
PMID: 36139853
Parkinson's disease (PD) is the second most common neurodegenerative movement disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Although a complex interplay of...
4.
Cai L, Arbab A, Lee T, Sharma A, Thomas B, Igarashi K, et al.
Free Radic Biol Med
. 2022 Jun;
188:134-145.
PMID: 35691510
Sepsis is a complex disease due to dysregulated host response to infection. Oxidative stress and mitochondrial dysfunction leading to metabolic dysregulation are among the hallmarks of sepsis. The transcription factor...
5.
Chu X, Subramani K, Thomas B, Terry Jr A, Fulzele S, Raju R
Aging Dis
. 2022 Apr;
13(2):568-582.
PMID: 35371607
Studies have shown that factors in the blood of young organisms can rejuvenate the old ones. Studies using heterochronic parabiosis models further reinforced the hypothesis that juvenile factors can rejuvenate...
6.
Poloznikov A, Nikulin S, Hushpulian D, Khristichenko A, Osipyants A, Asachenko A, et al.
Antioxidants (Basel)
. 2022 Feb;
11(2).
PMID: 35204103
To evaluate the differences in action of commercially available 2-oxoglutarate mimetics and "branched-tail" oxyquinoline inhibitors of hypoxia-inducible factor prolyl hydroxylase (HIF PHD), the inhibitors' IC values in the activation of...
7.
Popov A, Klimovich A, Styshova O, Tsybulsky A, Hushpulian D, Osipyants A, et al.
Molecules
. 2022 Feb;
27(3).
PMID: 35163891
Ginsenoside Rh2 increases the efficacy of doxorubicin (DOX) treatment in murine models of solid and ascites Ehrlich's adenocarcinoma. In a solid tumor model (treatment commencing 7 days after inoculation), DOX...
8.
Ahuja M, Kaidery N, Attucks O, McDade E, Hushpulian D, Gaisin A, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(45).
PMID: 34737234
9.
Gaisina I, Hushpulian D, Gaisin A, Kazakov E, Kaidery N, Ahuja M, et al.
Neurochem Int
. 2021 Jul;
149:105148.
PMID: 34329734
Aspirin is a desired leaving group in prodrugs aimed at treatment of neurodegeneration and other conditions. A library of aspirin derivatives of various scaffolds potentially activating Nrf2 has been tested...
10.
Thomas B, Coon J, Westfall H, Lee M
Cogn Sci
. 2021 Jul;
45(7):e13011.
PMID: 34213800
We study the wisdom of the crowd in three sequential decision-making tasks: the Balloon Analogue Risk Task (BART), optimal stopping problems, and bandit problems. We consider a behavior-based approach, using...