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Blessing Okai

Explore the profile of Blessing Okai including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 215
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Recent Articles
1.
Hoschler K, Maharjan S, Whitaker H, Southern J, Okai B, Baldevarona J, et al.
Vaccine . 2020 Feb; 38(12):2660-2670. PMID: 32070679
Background: The UK introduced quadrivalent live attenuated influenza vaccine (qLAIV) for children in 2013/2014. The impact of annual vaccination on effectiveness and immunogenicity is being assessed. Method: A phase III/IV...
2.
Gordon P, Okai B, Hoare J, Erwig L, Wilson H
J Leukoc Biol . 2016 Apr; 100(4):771-780. PMID: 27106674
Suppressor of cytokine signaling (SOCS) proteins are recognized as key feedback inhibitors modulating the inflammatory activities of macrophages, but comparatively little is known about whether and how they affect phagocytosis....
3.
Okai B, Lyall N, Gow N, Bain J, Erwig L
Infect Immun . 2015 Feb; 83(4):1523-35. PMID: 25644001
Avoidance of innate immune defense is an important mechanism contributing to the pathogenicity of microorganisms. The fungal pathogen Candida albicans undergoes morphogenetic switching from the yeast to the filamentous hyphal...
4.
Bain J, Louw J, Lewis L, Okai B, Walls C, Ballou E, et al.
mBio . 2014 Dec; 5(6):e01874. PMID: 25467440
Unlabelled: Candida albicans is a major life-threatening human fungal pathogen in the immunocompromised host. Host defense against systemic Candida infection relies heavily on the capacity of professional phagocytes of the...
5.
Lewis L, Bain J, Okai B, Gow N, Erwig L
J Vis Exp . 2013 Jan; (71). PMID: 23329139
Phagocytic clearance of fungal pathogens, and microorganisms more generally, may be considered to consist of four distinct stages: (i) migration of phagocytes to the site where pathogens are located; (ii)...
6.
Bain J, Lewis L, Okai B, Quinn J, Gow N, Erwig L
Fungal Genet Biol . 2012 Feb; 49(9):677-8. PMID: 22326419
Candida albicans is an opportunistic pathogen and is recognised and phagocytosed by macrophages. Using live-cell imaging, non-lytic expulsion/exocytosis of C. albicans from macrophages is demonstrated for the first time. Following...