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Blazej Ruszczycki

Explore the profile of Blazej Ruszczycki including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 882
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Recent Articles
1.
Piana K, Ziomber-Lisiak A, Ruszczycki B, Bugajski A, Szczerbowska-Boruchowska M
Arch Biochem Biophys . 2025 Feb; 765:110325. PMID: 39894381
In the presented study, we evaluated changes in the molecular structures of lipids and proteins in organs/tissues at the early stage of obesity induced by a high-calorie diet (HCD), using...
2.
Szczepankiewicz A, Parobczak K, Zareba-Koziol M, Ruszczycki B, Bijata M, Trzaskoma P, et al.
Biochim Biophys Acta Mol Cell Res . 2024 Aug; 1871(8):119829. PMID: 39197592
Nuclear speckles, also known as interchromatin granule clusters (IGCs), are subnuclear domains highly enriched in proteins involved in transcription and mRNA metabolism and, until recently, have been regarded primarily as...
3.
Das N, Baczynska E, Bijata M, Ruszczycki B, Zeug A, Plewczynski D, et al.
Neuroinformatics . 2022 Jun; 20(3):699. PMID: 35648272
No abstract available.
4.
Bijata M, Baczynska E, Muller F, Bijata K, Masternak J, Krzystyniak A, et al.
Cell Rep . 2022 Mar; 38(11):110532. PMID: 35294881
Major depressive disorder is a complex disease resulting from aberrant synaptic plasticity that may be caused by abnormal serotonergic signaling. Using a combination of behavioral, biochemical, and imaging methods, we...
5.
Das N, Baczynska E, Bijata M, Ruszczycki B, Zeug A, Plewczynski D, et al.
Neuroinformatics . 2021 Nov; 20(3):679-698. PMID: 34743262
Three-dimensional segmentation and analysis of dendritic spine morphology involve two major challenges: 1) how to segment individual spines from the dendrites and 2) how to quantitatively assess the morphology of...
6.
Skupien-Jaroszek A, Walczak A, Czaban I, Pels K, Szczepankiewicz A, Krawczyk K, et al.
PLoS One . 2021 Jun; 16(6):e0239111. PMID: 34086671
The Brain-Derived Neurotrophic Factor is one of the most important trophic proteins in the brain. The role of this growth factor in neuronal plasticity, in health and disease, has been...
7.
Baczynska E, Pels K, Basu S, Wlodarczyk J, Ruszczycki B
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33919977
Numerous brain diseases are associated with abnormalities in morphology and density of dendritic spines, small membranous protrusions whose structural geometry correlates with the strength of synaptic connections. Thus, the quantitative...
8.
Trzaskoma P, Ruszczycki B, Lee B, Pels K, Krawczyk K, Bokota G, et al.
Nat Commun . 2020 May; 11(1):2120. PMID: 32358536
The human genome is extensively folded into 3-dimensional organization. However, the detailed 3D chromatin folding structures have not been fully visualized due to the lack of robust and ultra-resolution imaging...
9.
Ruszczycki B, Pels K, Walczak A, Zamlynska K, Such M, Szczepankiewicz A, et al.
Front Neuroanat . 2019 Sep; 13:81. PMID: 31481881
The detailed architectural examination of the neuronal nuclei in any brain region, using confocal microscopy, requires quantification of fluorescent signals in three-dimensional stacks of confocal images. An essential prerequisite to...
10.
Skupio U, Tertil M, Bilecki W, Barut J, Korostynski M, Golda S, et al.
Neuropsychopharmacology . 2019 Jun; 45(2):404-415. PMID: 31254970
To date, neurons have been the primary focus of research on the role of glucocorticoids in the regulation of brain function and pathological behaviors, such as addiction. Astrocytes, which are...