Blake L Torrance
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Explore the profile of Blake L Torrance including associated specialties, affiliations and a list of published articles.
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13
Citations
60
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Recent Articles
1.
Wang B, Wang L, Gasek N, Kuo C, Nie J, Kim T, et al.
Cell Metab
. 2024 Aug;
36(8):1795-1805.e6.
PMID: 39111286
A key challenge in aging research is extending lifespan in tandem with slowing down functional decline so that life with good health (healthspan) can be extended. Here, we show that...
2.
Torrance B, Cadar A, Panier H, Martin D, Lorenzo E, Jellison E, et al.
Aging Cell
. 2024 May;
23(7):e14162.
PMID: 38689516
Clearance of senescent cells has demonstrated therapeutic potential in the context of chronic age-related diseases. Little is known, however, how clearing senescent cells affects the ability to respond to an...
3.
Lorenzo E, Torrance B, Haynes L
Front Aging
. 2023 Oct;
4:1161799.
PMID: 37886012
Cellular senescence has been implicated in the pathophysiology of many age-related diseases. However, it also plays an important protective role in the context of tumor suppression and wound healing. Reducing...
4.
Torrance B, Cadar A, Martin D, Panier H, Lorenzo E, Bartley J, et al.
Front Aging
. 2023 Jul;
4:1212750.
PMID: 37396956
Age is the greatest risk factor for adverse outcomes following influenza (flu) infection. The increased burden of senescent cells with age has been identified as a root cause in many...
5.
Keilich S, Cadar A, Ahern D, Torrance B, Lorenzo E, Martin D, et al.
Geroscience
. 2023 May;
45(5):3097.
PMID: 37256521
No abstract available.
6.
Martin D, Cadar A, Panier H, Torrance B, Kuchel G, Bartley J
Immun Ageing
. 2023 May;
20(1):18.
PMID: 37131271
Background: Aging is associated with progressive declines in immune responses leading to increased risk of severe infection and diminished vaccination responses. Influenza (flu) is a leading killer of older adults...
7.
Torrance B, Panier H, Cadar A, Martin D, Lorenzo E, Jellison E, et al.
bioRxiv
. 2023 Apr;
PMID: 37090607
Clearance of senescent cells has demonstrated therapeutic potential in the context of chronic age-related diseases. Little is known, however, how clearing senescent cells affects the ability to respond to an...
8.
Keilich S, Cadar A, Ahern D, Torrance B, Lorenzo E, Martin D, et al.
Geroscience
. 2022 Dec;
45(2):1197-1213.
PMID: 36580167
Older adults have diminished immune responses that increase susceptibility to infectious diseases, such as influenza (flu). In older adults, flu infection can lead to hospitalization, catastrophic disability, and mortality. We...
9.
Torrance B, Haynes L
Front Immunol
. 2022 Sep;
13:1006710.
PMID: 36119079
Aging results in systemic changes that leave older adults at much higher risk for adverse outcomes following respiratory infections. Much work has been done over the years to characterize and...
10.
Lorenzo E, Torrance B, Keilich S, Al-Naggar I, Harrison A, Xu M, et al.
Aging Cell
. 2021 Dec;
21(1):e13525.
PMID: 34962049
Aging and senescence impact CD4 T helper cell (Th) subset differentiation during influenza infection. In the lungs of infected aged mice, there were significantly greater percentages of Th cells expressing...