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Blaine A Christiansen

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Articles 77
Citations 3154
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Recent Articles
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Orr S, Pereira G, Christiansen B
J Orthop Surg Res . 2025 Jan; 20(1):125. PMID: 39891295
Background: Many orthopedic surgeons choose not to perform joint arthroplasty on patients with a Body Mass Index (BMI) of 35 or above, citing poorer outcomes and increased procedure risk. Identifying...
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McCool J, Sebastian A, Hum N, Wilson S, Davalos O, Murugesh D, et al.
PLoS One . 2025 Jan; 20(1):e0312587. PMID: 39752388
Post-traumatic osteoarthritis (PTOA) is a painful joint disease characterized by the degradation of bone, cartilage, and other connective tissues in the joint. PTOA is initiated by trauma to joint-stabilizing tissues,...
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Osipov B, Emami A, Cunningham H, Orr S, Lin Y, Jbeily E, et al.
JBMR Plus . 2024 Nov; 8(12):ziae135. PMID: 39605879
Femur fracture leads to loss of bone at uninjured skeletal sites, which may increase risk of subsequent fracture. Osteocytes, the most abundant bone cells, can directly resorb bone matrix and...
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Mendoza S, Wells K, Murugesh D, Hum N, Sebastian A, Gorman B, et al.
Bone . 2024 Nov; 192():117339. PMID: 39603372
Skeletal fracture resistance emerges from multiple components of bone structure like microarchitecture, matrix mineralization, and organization. These characteristics are engendered via mechanisms like the hypoxia-inducible factors (HIF) pathway, involving two...
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Saiz A, Rahmati M, Gresham R, Baldini T, Burgan J, Lee M, et al.
J Orthop Res . 2024 Nov; 43(3):603-616. PMID: 39550711
The field of bone regeneration has primarily focused on investigating fracture healing and nonunion in isolated musculoskeletal injuries. Compared to isolated fractures, which frequently heal well, fractures in patients with...
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Lin R, Osipov B, Steffen D, Chamberlin M, Pathak S, Christiansen B, et al.
Matrix Biol Plus . 2024 Jun; 23:100153. PMID: 38882396
Fish oils rank among the world's most popular nutritional supplements and are purported to have numerous health benefits. Previous work suggested that fish oils increase collagen production; however, the effect...
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Takahata K, Lin Y, Osipov B, Arakawa K, Enomoto S, Christiansen B, et al.
bioRxiv . 2024 May; PMID: 38766109
Objective: Anterior Cruciate Ligament (ACL) injury initiates post-traumatic osteoarthritis (PTOA) via two distinct processes: initial direct contact injury of the cartilage surface during ACL injury, and secondary joint instability due...
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Lin Y, Jbeily E, Tjandra P, Pride M, Lopez-Torres M, Elmankabadi S, et al.
Osteoarthritis Cartilage . 2024 May; 32(8):909-920. PMID: 38697509
Objective: People who sustain joint injuries such as anterior cruciate ligament (ACL) rupture often develop post-traumatic osteoarthritis (PTOA). In human patients, ACL injuries are often treated with ACL reconstruction. However,...
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Tjandra P, Ripplinger C, Christiansen B
Am J Physiol Heart Circ Physiol . 2024 Feb; 326(3):H845-H856. PMID: 38305753
Myocardial infarction (MI) and osteoporotic fracture (Fx) are two of the leading causes of mortality and morbidity worldwide. Although these traumatic injuries are treated as if they are independent, there...