Bjorn Wendik
Overview
Explore the profile of Bjorn Wendik including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
234
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0
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Recent Articles
1.
Quandt D, Dieter Zucht H, Amann A, Wulf-Goldenberg A, Borrebaeck C, Cannarile M, et al.
Oncotarget
. 2017 May;
8(29):48507-48520.
PMID: 28501851
During the last decade, novel immunotherapeutic strategies, in particular antibodies directed against immune checkpoint inhibitors, have revolutionized the treatment of different malignancies leading to an improved survival of patients. Identification...
2.
Ott E, Wendik B, Srivastava M, Pacho F, Tochterle S, Salvenmoser W, et al.
Dev Biol
. 2015 Oct;
411(1):101-14.
PMID: 26472045
Mutations in the homeobox transcription factor MNX1 are the major cause of dominantly inherited sacral agenesis. Studies in model organisms revealed conserved mnx gene requirements in neuronal and pancreatic development...
3.
Kotkamp K, Kur E, Wendik B, Polok B, Ben-Dor S, Onichtchouk D, et al.
PLoS One
. 2014 Mar;
9(3):e92356.
PMID: 24643012
Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in establishment of pluripotency. Here we investigated the control of myc gene...
4.
Arkhipova V, Wendik B, Devos N, Ek O, Peers B, Meyer D
Dev Biol
. 2012 Mar;
365(1):290-302.
PMID: 22426004
Differentiation of insulin producing beta-cells is a genetically well defined process that involves functions of various conserved transcription factors. Still, the transcriptional mechanisms underlying specification and determination of beta-cell fate...
5.
Belting H, Wendik B, Lunde K, Leichsenring M, Mossner R, Driever W, et al.
Dev Biol
. 2011 May;
356(2):323-36.
PMID: 21621531
Pou5f1/Oct-4 in mice is required for maintenance of embryonic pluripotent cell populations. Zebrafish pou5f1 maternal-zygotic mutant embryos (spiel ohne grenzen; MZspg) lack endoderm and have gastrulation and dorsoventral patterning defects....
6.
Epting D, Wendik B, Bennewitz K, Dietz C, Driever W, Kroll J
Circ Res
. 2010 May;
107(1):45-55.
PMID: 20466982
Rationale: Angiogenesis is regulated by the small GTPase Rac1. The ELMO1/DOCK180 complex forms a guanine nucleotide exchange factor for Rac1, regulating its activation during cell migration in different biological systems....
7.
Onichtchouk D, Geier F, Polok B, Messerschmidt D, Mossner R, Wendik B, et al.
Mol Syst Biol
. 2010 Mar;
6:354.
PMID: 20212526
The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time-resolved transcriptome analysis of zebrafish pou5f1 MZspg...
8.
Feldner J, Reimer M, Schweitzer J, Wendik B, Meyer D, Becker T, et al.
J Neurosci
. 2007 May;
27(18):4978-83.
PMID: 17475806
The pioneering primary motor axons in the zebrafish trunk are guided by multiple cues along their pathways. Plexins are receptor components for semaphorins that influence motor axon growth and path...
9.
Wendik B, Maier E, Meyer D
Dev Biol
. 2004 Apr;
268(2):372-83.
PMID: 15063174
The pancreas consists of two components, which exert distinct homeostatic function, an endocrine part that secretes hormones including insulin and an exocrine part that produces digestive enzymes. In mouse, one...