Biswajit Pradhan
Overview
Explore the profile of Biswajit Pradhan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
176
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0
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Recent Articles
1.
Pradhan B, Deep A, Konig J, Baaske M, Corbett K, Kim E
Mol Cell
. 2024 Dec;
85(1):107-116.e5.
PMID: 39626662
Structural maintenance of chromosomes (SMC) complexes play pivotal roles in genome organization and maintenance across all domains of life. In prokaryotes, SMC-family Wadjet complexes structurally resemble the widespread MukBEF but...
2.
Pradhan B, Pinto A, Kanno T, Tetiker D, Baaske M, Cutt E, et al.
bioRxiv
. 2024 Sep;
PMID: 39314301
Structural maintenance of chromosome (SMC) complexes organize and regulate genomes via DNA loop extrusion. During this process, the complexes increase the loop size by reeling in DNA from one or...
3.
Pradhan B, Deep A, Konig J, Baaske M, Corbett K, Kim E
bioRxiv
. 2024 Feb;
PMID: 38405785
Structural maintenance of chromosomes (SMC) protein complexes play pivotal roles in genome organization and maintenance across all domains of life. In prokaryotes, SMC family Wadjet complexes structurally resemble the widespread...
4.
Jeppsson K, Pradhan B, Sutani T, Sakata T, Umeda Igarashi M, Berta D, et al.
Mol Cell
. 2024 Jan;
84(5):867-882.e5.
PMID: 38295804
The structural maintenance of chromosomes (SMC) protein complexes-cohesin, condensin, and the Smc5/6 complex (Smc5/6)-are essential for chromosome function. At the molecular level, these complexes fold DNA by loop extrusion. Accordingly,...
5.
Barth R, Pradhan B, Kim E, Davidson I, van der Torre J, Peters J, et al.
Sci Rep
. 2023 Jul;
13(1):11616.
PMID: 37463951
No abstract available.
6.
Barth R, Pradhan B, Kim E, Davidson I, van der Torre J, Peters J, et al.
Sci Rep
. 2023 May;
13(1):8100.
PMID: 37208374
DNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The mechanism by which SMC motor proteins extrude DNA loops is still unresolved and...
7.
Pradhan B, Kanno T, Umeda Igarashi M, Loke M, Baaske M, Wong J, et al.
Nature
. 2023 Apr;
616(7958):843-848.
PMID: 37076626
Structural maintenance of chromosomes (SMC) protein complexes are essential for the spatial organization of chromosomes. Whereas cohesin and condensin organize chromosomes by extrusion of DNA loops, the molecular functions of...
8.
Pradhan B, Barth R, Kim E, Davidson I, Bauer B, van Laar T, et al.
Cell Rep
. 2022 Oct;
41(3):111491.
PMID: 36261017
Ring-shaped structural maintenance of chromosomes (SMC) complexes like condensin and cohesin extrude loops of DNA. It remains, however, unclear how they can extrude DNA loops in chromatin that is bound...
9.
Kim E, Martin Gonzalez A, Pradhan B, van der Torre J, Dekker C
Nat Struct Mol Biol
. 2022 Jul;
29(7):719-727.
PMID: 35835864
Condensin, a structural maintenance of chromosomes (SMC) complex, has been shown to be a molecular motor protein that organizes chromosomes by extruding loops of DNA. In cells, such loop extrusion...
10.
Tisma M, Panoukidou M, Antar H, Soh Y, Barth R, Pradhan B, et al.
Sci Adv
. 2022 Jun;
8(26):eabn3299.
PMID: 35767606
The ParAB system is essential for prokaryotic chromosome segregation. After loading at on the genome, ParB (partition protein B) proteins rapidly redistribute to distances of ~15 kilobases from the loading...