Birgit Kuhnapfel
Overview
Explore the profile of Birgit Kuhnapfel including associated specialties, affiliations and a list of published articles.
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8
Citations
359
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Recent Articles
1.
Renzaho A, Podlech J, Kuhnapfel B, Blaum F, Reddehase M, Lemmermann N
Front Cell Infect Microbiol
. 2020 May;
10:138.
PMID: 32373544
Reactivation of latent cytomegalovirus (CMV) in recipients of hematopoietic cell transplantation (HCT) not only results in severe organ manifestations, but can also cause "graft failure" resulting in bone marrow (BM)...
2.
Renzaho A, Schmiedeke J, Griessl M, Kuhnapfel B, Seckert C, Lemmermann N
Med Microbiol Immunol
. 2019 Apr;
208(3-4):439-446.
PMID: 31004200
Roizman's definition of herpesviral latency, which applies also to cytomegaloviruses (CMVs), demands maintenance of reactivation-competent viral genomes after clearance of productive infection. It is more recent understanding that failure to...
3.
Seckert C, Griessl M, Buttner J, Scheller S, Simon C, Kropp K, et al.
Med Microbiol Immunol
. 2012 Sep;
201(4):551-66.
PMID: 22991040
Low public awareness of cytomegalovirus (CMV) results from the only mild and transient symptoms that it causes in the healthy immunocompetent host, so that primary infection usually goes unnoticed. The...
4.
Kropp K, Simon C, Fink A, Renzaho A, Kuhnapfel B, Podlech J, et al.
J Gen Virol
. 2009 Jun;
90(Pt 10):2395-2401.
PMID: 19553390
Major immediate-early (MIE) transcriptional enhancers of cytomegaloviruses are key regulators that are regarded as determinants of virus replicative fitness and pathogenicity. The MIE locus of murine cytomegalovirus (mCMV) shows bidirectional...
5.
Seckert C, Renzaho A, Tervo H, Krause C, Deegen P, Kuhnapfel B, et al.
J Virol
. 2009 Jun;
83(17):8869-84.
PMID: 19535440
Latent cytomegalovirus (CMV) is frequently transmitted by organ transplantation, and its reactivation under conditions of immunosuppressive prophylaxis against graft rejection by host-versus-graft disease bears a risk of graft failure due...
6.
Holtappels R, Simon C, Munks M, Thomas D, Deegen P, Kuhnapfel B, et al.
J Virol
. 2008 Mar;
82(12):5781-96.
PMID: 18367531
Cytomegalovirus (CMV) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitution of...
7.
Simon C, Kuhnapfel B, Reddehase M, Grzimek N
J Virol
. 2007 May;
81(14):7805-10.
PMID: 17494084
Enhancers are defined as DNA elements that increase transcription when placed in any orientation relative to a promoter. The major immediate-early (MIE) enhancer region of murine cytomegalovirus is flanked by...
8.
Simon C, Holtappels R, Tervo H, Bohm V, Daubner T, Oehrlein-Karpi S, et al.
J Virol
. 2006 Aug;
80(21):10436-56.
PMID: 16928768
During murine cytomegalovirus (mCMV) latency in the lungs, most of the viral genomes are transcriptionally silent at the major immediate-early locus, but rare and stochastic episodes of desilencing lead to...