Binhua Tang
Overview
Explore the profile of Binhua Tang including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
142
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0
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Recent Articles
1.
Tang B, Chen Y
BMC Bioinformatics
. 2025 Feb;
26(1):62.
PMID: 39994539
Background: Advancements in high-throughput sequencing and deep learning have boosted single-cell RNA studies. However, current methods for annotating single-cell data face challenges due to high data sparsity and tedious manual...
2.
Tang B, Chen Y, Wang Y, Nie J
Biomed Res Int
. 2021 Oct;
2021:7865856.
PMID: 34697591
Genome-wide omics technology boosts deep interrogation into the clinical prognosis and inherent mechanism of pancreatic oncology. Classic LASSO methods coequally treat all candidates, ignoring individual characteristics, thus frequently deteriorating performance...
3.
Tang B, Wang Y, Chen Y, Li M, Tao Y
Front Cell Dev Biol
. 2021 Feb;
8:620746.
PMID: 33585460
Carcinoma diagnosis and prognosis are still hindered by the lack of effective prediction model and integration methodology. We proposed a novel feature selection with orthogonal regression (FSOR) method to resolve...
4.
Tang B, Pan Z, Yin K, Khateeb A
Front Genet
. 2019 Apr;
10:214.
PMID: 30972100
Extracting inherent valuable knowledge from omics big data remains as a daunting problem in bioinformatics and computational biology. Deep learning, as an emerging branch from machine learning, has exhibited unprecedented...
5.
Tang B
Biomed Res Int
. 2018 Jul;
2018:7602794.
PMID: 30035125
Intercellular crosstalk effects between DNA methylation and lncRNA regulation remain elusive in lung carcinoma epigenetics. We present an application toolkit MetLnc in integration and annotation for group-wise NSCLC tissue-based DNA...
6.
Tang B, Cheng X, Xi Y, Chen Z, Zhou Y, Jin V
Genes (Basel)
. 2017 Sep;
8(9).
PMID: 28885554
Recent sequence-based profiling technologies such as high-throughput sequencing to detect fragment nucleotide sequence (Hi-C) and chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) have revolutionized the field of three-dimensional (3D)...
7.
Tang B, Zhou Y, Wang C, Huang T, Jin V
Sci Rep
. 2017 Jun;
7(1):3626.
PMID: 28620196
Despite numerous studies done on understanding the role of DNA methylation, limited work has focused on systems integration of cell type-specific interplay between DNA methylation and gene transcription. Through a...
8.
Tang B, Wang X, Jin V
Biomed Res Int
. 2017 Mar;
2017:5346793.
PMID: 28357402
Sequencing data quality and peak alignment efficiency of ChIP-sequencing profiles are directly related to the reliability and reproducibility of NGS experiments. Till now, there is no tool specifically designed for...
9.
Tang B
Biomed Res Int
. 2017 Jan;
2016:1597489.
PMID: 28116291
Genome-wide deciphering intercellular differential DNA methylation as well as its roles in transcriptional regulation remains elusive in cancer epigenetics. Here we developed a toolkit META2 for DNA methylation annotation and...
10.
Tang B
Bioengineered
. 2016 Oct;
8(3):248-255.
PMID: 27690208
Enhanced accuracy and high-throughput capability in capturing genetic activities lead ChIP-sequencing technology to be applied prevalently in diverse study for tackling DNA-protein interaction problems. Till now, such questions as deciding...