Bingshan Li
Overview
Explore the profile of Bingshan Li including associated specialties, affiliations and a list of published articles.
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127
Citations
5379
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Recent Articles
1.
Jia G, Chen Z, Ping J, Cai Q, Tao R, Li C, et al.
Nat Genet
. 2025 Jan;
57(1):80-87.
PMID: 39753771
Genome-wide association studies have identified approximately 200 genetic risk loci for breast cancer, but the causal variants and target genes are mostly unknown. We sought to fine-map all known breast...
2.
Wang C, Markus H, Diwadkar A, Khunsriraksakul C, Carrel L, Li B, et al.
Nat Commun
. 2025 Jan;
16(1):180.
PMID: 39747168
Autoimmune diseases often exhibit a preclinical stage before diagnosis. Electronic health record (EHR) based-biobanks contain genetic data and diagnostic information, which can identify preclinical individuals at risk for progression. Biobanks...
3.
Niu W, Yu S, Li X, Wang Z, Chen R, Michalski C, et al.
bioRxiv
. 2024 Oct;
PMID: 39416123
Tuberous Sclerosis Complex (TSC), an autosomal dominant condition, is caused by heterozygous mutations in either the or genes, manifesting in systemic growth of benign tumors. In addition to brain lesions,...
4.
Jia G, Ping J, Guo X, Yang Y, Tao R, Li B, et al.
Nat Genet
. 2024 May;
56(5):819-826.
PMID: 38741014
We performed genome-wide association studies of breast cancer including 18,034 cases and 22,104 controls of African ancestry. Genetic variants at 12 loci were associated with breast cancer risk (P < ...
5.
Ping J, Jia G, Cai Q, Guo X, Tao R, Ambrosone C, et al.
Nat Commun
. 2024 May;
15(1):3718.
PMID: 38697998
African-ancestry (AA) participants are underrepresented in genetics research. Here, we conducted a transcriptome-wide association study (TWAS) in AA female participants to identify putative breast cancer susceptibility genes. We built genetic...
6.
Yan C, Grabowska M, Dickson A, Li B, Wen Z, Roden D, et al.
NPJ Digit Med
. 2024 Feb;
7(1):46.
PMID: 38409350
Drug repurposing represents an attractive alternative to the costly and time-consuming process of new drug development, particularly for serious, widespread conditions with limited effective treatments, such as Alzheimer's disease (AD)....
7.
Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia
Ochs-Balcom H, Preus L, Du Z, Elston R, Teerlink C, Jia G, et al.
Hum Mol Genet
. 2024 Jan;
33(8):687-697.
PMID: 38263910
Background: Expansion of genome-wide association studies across population groups is needed to improve our understanding of shared and unique genetic contributions to breast cancer. We performed association and replication studies...
8.
Zhang Z, Luo R, Kelly W, Chen J, Donahue S, Ip K, et al.
Prostate Cancer Prostatic Dis
. 2023 Dec;
27(2):339-347.
PMID: 38057610
Background: Identification of emerging molecular biomarkers on circulating tumor cells (CTCs) represents an attractive feature of liquid biopsy that facilitates precision and tailored medicine in the management of metastatic castration-resistant...
9.
Liang Q, Jiang Y, Shieh A, Zhou D, Chen R, Wang F, et al.
bioRxiv
. 2023 Oct;
PMID: 37873195
Background: The impact of genetic variants on gene expression has been intensely studied at the transcription level, yielding in valuable insights into the association between genes and the risk of...
10.
Xu G, Loberg M, Gallant J, Sheng Q, Chen S, Lehmann B, et al.
Cell Genom
. 2023 Oct;
3(10):100409.
PMID: 37868034
Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet, thyroid cancer management is largely guided by staging and histology, with few molecular prognostic and treatment biomarkers. Here,...