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Biki Gupta

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Articles 35
Citations 489
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Recent Articles
1.
Boonchalermvichian C, Yan H, Gupta B, Rubin A, Baker J, Negrin R
Front Transplant . 2024 Jul; 3:1353803. PMID: 38993780
Invariant Natural Killer T cell therapy is an emerging platform of immunotherapy for cancer treatment. This unique cell population is a promising candidate for cell therapy for cancer treatment because...
2.
Gupta B, Rai R, Pal P, Rossmiller D, Chaudhary S, Chiaro A, et al.
Cells . 2024 May; 13(9. PMID: 38727292
Integrin αβ+ T cells perpetuate tissue injury in chronic inflammatory diseases, yet their role in hepatic fibrosis progression remains poorly understood. Here, we report increased accumulation of αβ+ T cells...
3.
Gupta B, Rai R, Pal P, Chaudhary S, Chiaro A, Seaman S, et al.
bioRxiv . 2023 Mar; PMID: 36865167
Integrin α β + T cells perpetuate tissue injury in chronic inflammatory diseases, yet their role in hepatic fibrosis progression remains poorly understood. Here we report increased accumulation of α...
4.
Gupta B, Rai R, Oertel M, Raeman R
Semin Liver Dis . 2022 Jun; 42(2):122-137. PMID: 35738255
Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of progressive liver diseases ranging from simple steatosis to steatohepatitis and fibrosis. Globally, NAFLD is the leading cause of morbidity and mortality...
5.
Choi Y, Jang H, Gupta B, Jeong J, Ge Y, Yong C, et al.
J Hematol Oncol . 2020 Sep; 13(1):123. PMID: 32928251
Background: Conventional therapeutic approaches for tumor angiogenesis, which are primarily focused on the inhibition of active angiogenesis to starve cancerous cells, target the vascular endothelial growth factor signaling pathway. This...
6.
Gautam M, Gupta B, Soe Z, Poudel K, Maharjan S, Jeong J, et al.
Pharm Res . 2020 Aug; 37(8):162. PMID: 32749542
Purpose: The goal of this study was to develop chemotherapeutic drug-loaded photoactivable stealth polymer-coated silica based- mesoporous titania nanoplatforms for enhanced antitumor activity. Methods: Both in vitro and in vivo...
7.
Rai R, Liu Y, Iyer S, Liu S, Gupta B, Desai C, et al.
J Hepatol . 2020 Jun; 73(5):1013-1022. PMID: 32540177
Background & Aims: The heterodimeric integrin receptor αβ regulates CD4 T cell recruitment to inflamed tissues, but its role in the pathogenesis of non-alcoholic steatohepatitis (NASH) is unknown. Herein, we...
8.
Gupta B, Liu Y, Chopyk D, Rai R, Desai C, Kumar P, et al.
FASEB J . 2020 Apr; 34(5):7089-7102. PMID: 32275114
There is compelling evidence implicating intestinal permeability in the pathogenesis of nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain poorly understood. Here we examined the role of bile acids (BA)...
9.
Gautam M, Thapa R, Gupta B, Soe Z, Ou W, Poudel K, et al.
Expert Opin Drug Deliv . 2020 Feb; 17(3):423-434. PMID: 32028805
: Phytosterols significantly reduce the risk of cancer by directly inhibiting tumor growth, inducing apoptosis, and inhibiting tumor metastasis. Stigmasterol (STS), a phytosterol, exhibits anticancer effects against various cancers, including...
10.
Ou W, Byeon J, Soe Z, Kim B, Thapa R, Gupta B, et al.
Theranostics . 2019 Oct; 9(23):6780-6796. PMID: 31660068
Several therapeutic nanosystems have been engineered to remedy the shortcomings of cancer monotherapies, including immunotherapy (stimulating the host immune system to eradicate cancer), to improve therapeutic efficacy with minimizing off-target...