Bidur Bhandary
Overview
Explore the profile of Bidur Bhandary including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
423
Followers
0
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Recent Articles
1.
Perez-Bonilla P, LaViolette B, Bhandary B, Ullas S, Chen X, Hirenallur-Shanthappa D
PLoS One
. 2024 Jul;
19(7):e0307467.
PMID: 39038017
Heart Failure (HF) continues to be a complex public health issue with increasing world population prevalence. Although overall mortality has decreased for HF and hypertrophic cardiomyopathy (HCM), a precursor for...
2.
Li S, Bhandary B, Gu X, DeFalco T
Proc Natl Acad Sci U S A
. 2022 Oct;
119(41):e2213026119.
PMID: 36194632
Supporting cells of the ovary, termed granulosa cells, are essential for ovarian differentiation and oogenesis by providing a nurturing environment for oocyte maintenance and maturation. Granulosa cells are specified in...
3.
MacDonald B, Keshishian H, Mundorff C, Arduini A, Lai D, Bendinelli K, et al.
Mol Cell Proteomics
. 2022 Mar;
21(4):100223.
PMID: 35283288
Loss-of-function mutations in the secreted enzyme ADAMTS7 (a disintegrin and metalloproteinase with thrombospondin motifs 7) are associated with protection for coronary artery disease. ADAMTS7 catalytic inhibition has been proposed as...
4.
Heinrich A, Bhandary B, Potter S, Ratner N, DeFalco T
Cell Rep
. 2021 Oct;
37(4):109885.
PMID: 34706238
Sertoli cells are highly polarized testicular supporting cells that simultaneously nurture multiple stages of germ cells during spermatogenesis. Proper localization of polarity protein complexes within Sertoli cells, including those responsible...
5.
Mizoguchi T, MacDonald B, Bhandary B, Popp N, Laprise D, Arduini A, et al.
Circ Res
. 2021 Jun;
129(4):458-470.
PMID: 34176299
[Figure: see text].
6.
Meng Q, Bhandary B, Bhuiyan M, James J, Osinska H, Valiente-Alandi I, et al.
Circ Res
. 2018 Dec;
123(12):1285-1297.
PMID: 30566042
Rationale: Hypertrophic cardiomyopathy occurs with a frequency of about 1 in 500 people. Approximately 30% of those affected carry mutations within the gene encoding cMyBP-C (cardiac myosin binding protein C)....
7.
Bhandary B, Meng Q, James J, Osinska H, Gulick J, Valiente-Alandi I, et al.
J Am Heart Assoc
. 2018 Oct;
7(20):e010013.
PMID: 30371263
Background Transforming growth factor beta ( TGF -β) is an important cytokine in mediating the cardiac fibrosis that often accompanies pathogenic cardiac remodeling. Cardiomyocyte-specific expression of a mutant αB-crystallin (Cry...
8.
Kim H, Lee G, Bhattarai K, Junjappa R, Lee H, Handigund M, et al.
Exp Mol Med
. 2018 Mar;
50(2):e444.
PMID: 29504610
Hyperactivation of phosphoinositol 3-kinase (PI3K) has been suggested to be a potential mechanism for endoplasmic reticulum (ER) stress-enhanced airway hyperresponsiveness, and PI3K inhibitors have been examined as asthma therapeutics. However,...
9.
Meng Q, Bhandary B, Osinska H, James J, Xu N, Shay-Winkler K, et al.
J Am Heart Assoc
. 2017 Sep;
6(9).
PMID: 28871043
Background: Cardiac stress can trigger production of a 40-kDa peptide fragment derived from the amino terminus of the cardiac myosin-binding protein C. Cardiac stress, as well as cMyBP-C mutations, can...
10.
Bhuiyan M, McLendon P, James J, Osinska H, Gulick J, Bhandary B, et al.
Pflugers Arch
. 2016 Aug;
468(10):1685-95.
PMID: 27568194
Cardiac myosin-binding protein C (cMyBP-C) is an integral part of the sarcomeric machinery in cardiac muscle that enables normal function. cMyBP-C regulates normal cardiac contraction by functioning as a brake...