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Bianka M Zanini

Explore the profile of Bianka M Zanini including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 96
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Recent Articles
11.
Isola J, Veiga G, de Brito C, Alvarado-Rincon J, Garcia D, Zanini B, et al.
Geroscience . 2022 Jun; 45(4):2109-2120. PMID: 35689785
17α-estradiol (17α-E2) is referred to as a nonfeminizing estrogen that was recently found to extend healthspan and lifespan in male, but not female, mice. Despite an abundance of data indicating...
12.
Hense J, Garcia D, Isola J, Alvarado-Rincon J, Zanini B, Prosczek J, et al.
Geroscience . 2022 Apr; 44(3):1747-1759. PMID: 35460445
Senescent cells are in a cell cycle arrest state and accumulate with aging and obesity, contributing to a chronic inflammatory state. Treatment with senolytic drugs dasatinib and quercetin (D + ...
13.
Isola J, Zanini B, Hense J, Alvarado-Rincon J, Garcia D, Pereira G, et al.
Exp Gerontol . 2022 Jan; 159:111669. PMID: 35032571
Calorie restriction (CR) (25-40%) is the most commonly studied strategy for curtailing age-related disease and has also been found to extend reproductive lifespan in female mice. However, the effects of...
14.
Zanini B, Andrade K, Pradiee J, Veiga G, Garcia D, Mondadori R, et al.
Reprod Fertil Dev . 2020 Nov; 32(18):1338-1349. PMID: 33243369
The aim of this study was to investigate the effect of calorie restriction (CR) during pregnancy in mice on metabolism and ovarian function in the offspring. Pregnant female mice were...
15.
Schneider A, Saccon T, Garcia D, Zanini B, Isola J, Hense J, et al.
J Gerontol A Biol Sci Med Sci . 2020 Oct; 76(9):1579-1586. PMID: 33037434
The mammalian female is born with a limited ovarian reserve of primordial follicles. These primordial follicles are slowly activated throughout the reproductive lifecycle, thereby determining lifecycle length. Once primordial follicles...
16.
Isola J, Zanini B, Sidhom S, Kopchick J, Bartke A, Masternak M, et al.
Exp Gerontol . 2019 Nov; 129:110769. PMID: 31698046
Growth hormone receptor knockout mice (GHRKO) have reduced body size and increased insulin sensitivity. These mice are known for having extended lifespan, healthspan and female reproductive longevity. Seventeen α-estradiol (17α-E2)...