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Bhargavi Natarajan

Explore the profile of Bhargavi Natarajan including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 71
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Recent Articles
1.
Khan A, Sundar P, Natarajan B, Gupta V, Arige V, Reddy S, et al.
J Mol Cell Cardiol . 2021 Jun; 158:140-152. PMID: 34081950
3-Hydroxy-3-methyl glutaryl-coenzyme A reductase (Hmgcr) encodes the rate-limiting enzyme in the cholesterol biosynthesis pathway. The regulation of Hmgcr in rat models of genetic hypertension (viz. Spontaneously Hypertensive Rat [SHR] and...
2.
Natarajan B, Arige V, Khan A, Reddy S, Barthwal M, Mahapatra N
Hypertens Res . 2020 Sep; 44(2):154-167. PMID: 32917968
Kidneys have a high resting metabolic rate and low partial pressure of oxygen due to enhanced mitochondrial oxygen consumption and ATP production needed for active solute transport. Heightened mitochondrial activity...
3.
Khan A, Agarwal H, Reddy S, Arige V, Natarajan B, Gupta V, et al.
Mol Cell Biol . 2020 Feb; 40(9). PMID: 32071155
Hypercholesterolemia is a strong predictor of cardiovascular diseases. The 3-hydroxy-3-methylglutaryl coenzyme A reductase gene () coding for the rate-limiting enzyme in the cholesterol biosynthesis pathway is a crucial regulator of...
4.
Arige V, Agarwal A, Khan A, Kalyani A, Natarajan B, Gupta V, et al.
J Mol Biol . 2019 Feb; 431(6):1127-1147. PMID: 30738894
Monoamine oxidase B (MAO-B), a flavoenzyme located in the outer mitochondrial membrane, is involved in the catabolism of monoamines. Altered levels of MAO-B are associated with cardiovascular/neuronal diseases. However, molecular...
5.
Sonawane P, Gupta V, Sasi B, Kalyani A, Natarajan B, Khan A, et al.
Biochemistry . 2014 Oct; 53(44):6878-92. PMID: 25295465
Renalase, a novel monoamine oxidase, is emerging as an important regulator of cardiovascular, metabolic, and renal diseases. However, the mechanism of transcriptional regulation of this enzyme remains largely unknown. We...
6.
Ramisetty B, Natarajan B, Santhosh R
Crit Rev Microbiol . 2013 Jun; 41(1):89-100. PMID: 23799870
Toxin-antitoxin (TA) systems consist of a bicistronic operon, encoding a toxin and an antitoxin. They are widely distributed in the prokaryotic kingdom, often in multiple numbers. TAs are implicated in...