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Beverly S Franek

Explore the profile of Beverly S Franek including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 856
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Recent Articles
1.
Patterson K, Franek B, Muller-Quernheim J, Sperling A, Sweiss N, Niewold T
Cytokine . 2013 Feb; 61(3):906-11. PMID: 23384655
Aims: Sarcoidosis is a granulomatous disease of unknown etiology marked by tremendous clinical heterogeneity. Many patients enter remission with good long-term outcomes. Yet, chronic disease is not uncommon, and this...
2.
Vazgiourakis V, Zervou M, Eliopoulos E, Sharma S, Sidiropoulos P, Franek B, et al.
Clin Exp Rheumatol . 2012 Nov; 31(1):97-102. PMID: 23111153
Objectives: VEGFR2 gene polymorphisms have already been correlated with vascular diseases such as coronary heart disease (CHD) and may influence endothelial integrity, repair and function. In view of the premature...
3.
Koldobskaya Y, Ko K, Kumar A, Agik S, Arrington J, Kariuki S, et al.
Clin Dev Immunol . 2012 Sep; 2012:682018. PMID: 22988468
Systemic lupus erythematosus (SLE) is a highly heterogeneous autoimmune disorder characterized by differences in autoantibody profiles, serum cytokines, and clinical manifestations. We have previously conducted a case-case genome-wide association study...
4.
Jensen M, Patterson K, Kumar A, Kumabe M, Franek B, Niewold T
Ann Rheum Dis . 2012 Aug; 72(4):596-601. PMID: 22904259
Objective: Hyperactivity of the type I interferon (IFN) pathway is involved in the pathogenesis of systemic lupus erythematosus (SLE). Immunoglobulin like transcript (ILT3) is an immunohibitory transmembrane molecule which is...
5.
Feng X, Han D, Kilaru B, Franek B, Niewold T, Reder A
Arch Neurol . 2012 Jul; 69(10):1303-9. PMID: 22801747
Objective: To determine whether statins affect type 1 interferon responses in relapsing-remitting multiple sclerosis (RRMS). Design: Study effects of atorvastatin on type 1 interferon responses in Jurkat cells, mononuclear cells...
6.
Cherian T, Kariuki S, Franek B, Buyon J, Clancy R, Niewold T
Arthritis Rheum . 2012 Jun; 64(10):3383-7. PMID: 22674082
Objective: Variation in the interferon regulatory factor 5 (IRF5) gene has been associated with risk of developing systemic lupus erythematosus (SLE), and this association is largely dependent upon anti-Ro autoantibodies....
7.
Ko K, Franek B, Marion M, Kaufman K, Langefeld C, Harley J, et al.
J Rheumatol . 2012 Apr; 39(6):1238-40. PMID: 22505704
Objective: To investigate and refine the relationships among systemic lupus erythematosus (SLE) and related autoantibodies, interferon-α (IFN-α), and various ancestral backgrounds. Methods: We investigated quantitatively defined genetic ancestry through principal...
8.
Weckerle C, Mangale D, Franek B, Kelly J, Kumabe M, James J, et al.
Arthritis Rheum . 2012 Apr; 64(9):2947-52. PMID: 22488302
Objective: Systemic lupus erythematosus (SLE) disease manifestations are highly variable among patients, and the prevalence of individual clinical features differs significantly by ancestry. Serum tumor necrosis factor α (TNFα) levels...
9.
Sweiss N, Zhang W, Franek B, Kariuki S, Moller D, Patterson K, et al.
PLoS One . 2011 Dec; 6(12):e29126. PMID: 22195005
Background: Both type I interferon (IFN), also known as IFN-α and tumor necrosis factor alpha (TNF-α) have been implicated in the pathogenesis of sarcoidosis. We investigated serum levels of these...
10.
Trivedi T, Franek B, Green S, Kariuki S, Kumabe M, Mikolaitis R, et al.
J Biomed Biotechnol . 2011 Dec; 2011:802581. PMID: 22131818
Variants of the osteopontin (OPN) gene have been associated with systemic lupus erythematosus (SLE) susceptibility and cytokine profiles in SLE patients. It is not known whether these alleles are associated...