Bettina Kempkes
Overview
Explore the profile of Bettina Kempkes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
37
Citations
1414
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dietz A, Subedi P, Azimzadeh O, Duchrow L, Kaestle F, Paetzold J, et al.
Biomark Insights
. 2024 Nov;
19:11772719241274017.
PMID: 39493730
Background: Sensitivity to ionizing radiation differs between individuals, but there is a limited understanding of the biological mechanisms that account for these variations. One example of such mechanisms are the...
2.
Beer S, Wange L, Zhang X, Kuklik-Roos C, Enard W, Hammerschmidt W, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(30):e2200512119.
PMID: 35857872
Epstein-Barr virus (EBV) is a human tumor virus which preferentially infects resting human B cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent protein EBV...
3.
Zhang X, Schuhmachers P, Mourao A, Giansanti P, Murer A, Thumann S, et al.
EMBO Rep
. 2021 Oct;
22(12):e53007.
PMID: 34605140
While Epstein-Barr virus (EBV) establishes a life-long latent infection in apparently healthy human immunocompetent hosts, immunodeficient individuals are at particular risk to develop lymphoproliferative B-cell malignancies caused by EBV. A...
4.
Anastasiadou E, Stroopinsky D, Alimperti S, Jiao A, Pyzer A, Cippitelli C, et al.
Leukemia
. 2018 Jun;
33(1):132-147.
PMID: 29946193
Cancer cells subvert host immune surveillance by altering immune checkpoint (IC) proteins. Some Epstein-Barr virus (EBV)-associated tumors have higher Programmed Cell Death Ligand, PD-L1 expression. However, it is not known...
5.
Glaser L, Rieger S, Thumann S, Beer S, Kuklik-Roos C, Martin D, et al.
PLoS Pathog
. 2017 Oct;
13(10):e1006664.
PMID: 28968461
Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays a key role in this process....
6.
Ghosh S, Honscheid A, Duckers G, Ginzel S, Gohlke H, Gombert M, et al.
Haematologica
. 2016 Dec;
102(2):e69-e72.
PMID: 27979922
No abstract available.
7.
Daschkey S, Bienemann K, Schuster V, Kreth H, Linka R, Honscheid A, et al.
J Clin Immunol
. 2016 Jul;
36(7):684-92.
PMID: 27473539
Hereditary defects in several genes have been shown to disturb the normal immune response to EBV and to give rise to severe EBV-induced lymphoproliferation in the recent years. Nevertheless, in...
8.
Gunnell A, Webb H, Wood C, McClellan M, Wichaidit B, Kempkes B, et al.
Nucleic Acids Res
. 2016 Feb;
44(10):4636-50.
PMID: 26883634
In B cells infected by the cancer-associated Epstein-Barr virus (EBV), RUNX3 and RUNX1 transcription is manipulated to control cell growth. The EBV-encoded EBNA2 transcription factor (TF) activates RUNX3 transcription leading...
9.
Kalchschmidt J, Gillman A, Paschos K, Bazot Q, Kempkes B, Allday M
PLoS Pathog
. 2016 Jan;
12(1):e1005383.
PMID: 26751214
It is well established that Epstein-Barr virus nuclear antigen 3C (EBNA3C) can act as a potent repressor of gene expression, but little is known about the sequence of events occurring...
10.
Kempkes B, Robertson E
Curr Opin Virol
. 2015 Oct;
14:138-44.
PMID: 26453799
EBV drives resting B cells to continuous proliferating latently infected cells. A restricted program of viral transcription contributes to latency and cell proliferation important for growth transformation. Recent interest in...