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Berwini Endaya

Explore the profile of Berwini Endaya including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 764
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Recent Articles
1.
Bielcikova Z, Stursa J, Krizova L, Dong L, Spacek J, Hlousek S, et al.
EClinicalMedicine . 2023 Apr; 57:101873. PMID: 37064512
Background: Mitochondria present an emerging target for cancer treatment. We have investigated the effect of mitochondrially targeted tamoxifen (MitoTam), a first-in-class anti-cancer agent, in patients with solid metastatic tumours. Methods:...
2.
Oh S, Jo S, Kim H, Mai V, Endaya B, Neuzil J, et al.
Anal Chem . 2023 Jan; 95(2):1184-1192. PMID: 36602057
Early diagnosis of hepatocellular carcinoma (HCC) is difficult; the lack of convenient biomarker-based diagnostic modalities renders high-risk HCC patients burdened by life-long periodical examinations. Here, a new chemical biopsy approach...
3.
Vacurova E, Trnovska J, Svoboda P, Skop V, Novosadova V, Reguera D, et al.
Nat Commun . 2022 Apr; 13(1):1866. PMID: 35387987
Type 2 diabetes mellitus represents a major health problem with increasing prevalence worldwide. Limited efficacy of current therapies has prompted a search for novel therapeutic options. Here we show that...
4.
Stemberkova-Hubackova S, Zobalova R, Dubisova M, Smigova J, Dvorakova S, Korinkova K, et al.
Clin Transl Med . 2022 Mar; 12(3):e645. PMID: 35352502
No abstract available.
5.
Bajzikova M, Kovarova J, Coelho A, Boukalova S, Oh S, Rohlenova K, et al.
Cell Metab . 2018 Nov; 29(2):399-416.e10. PMID: 30449682
Cancer cells without mitochondrial DNA (mtDNA) do not form tumors unless they reconstitute oxidative phosphorylation (OXPHOS) by mitochondria acquired from host stroma. To understand why functional respiration is crucial for...
6.
Endaya B, Guan S, Newman J, Huynh H, Sia K, Chong S, et al.
Oncotarget . 2017 Sep; 8(33):54629-54639. PMID: 28903370
The epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein that is regarded as one of the markers for tumor initiating cells (TIC) in human hepatocellular carcinoma (HCC)....
7.
Dong L, Kovarova J, Bajzikova M, Bezawork-Geleta A, Svec D, Endaya B, et al.
Elife . 2017 Feb; 6. PMID: 28195532
Recently, we showed that generation of tumours in syngeneic mice by cells devoid of mitochondrial (mt) DNA (ρ cells) is linked to the acquisition of the host mtDNA. However, the...
8.
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, et al.
Antioxid Redox Signal . 2016 Jul; 26(2):84-103. PMID: 27392540
Aims: Expression of the HER2 oncogene in breast cancer is associated with resistance to treatment, and Her2 may regulate bioenergetics. Therefore, we investigated whether disruption of the electron transport chain...
9.
Endaya B, Cavanagh B, Alowaidi F, Walker T, de Pennington N, Ng J, et al.
J Neurosci Methods . 2015 Oct; 257:121-33. PMID: 26432933
Background: The characterisation of dividing brain cells is fundamental for studies ranging from developmental and stem cell biology, to brain cancers. Whilst there is extensive anatomical data on these dividing...
10.
Tan A, Baty J, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, et al.
Cell Metab . 2015 Jan; 21(1):81-94. PMID: 25565207
We report that tumor cells without mitochondrial DNA (mtDNA) show delayed tumor growth, and that tumor formation is associated with acquisition of mtDNA from host cells. This leads to partial...