Bertille Montibus
Overview
Explore the profile of Bertille Montibus including associated specialties, affiliations and a list of published articles.
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14
Citations
102
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Recent Articles
1.
Brempou D, Montibus B, Izatt L, Andoniadou C, Oakey R
Sci Rep
. 2024 Dec;
14(1):29958.
PMID: 39622952
Despite the prevalence of sequencing data in biomedical research, the methylome remains underrepresented. Given the importance of DNA methylation in gene regulation and disease, it is crucial to address the...
2.
Montibus B, Cain J, Martinez-Nunez R, Oakey R
Genome Res
. 2024 Nov;
34(12):2163-2175.
PMID: 39578100
Nucleotide sequences along a gene provide instructions to transcriptional and cotranscriptional machinery allowing genome expansion into the transcriptome. Nucleotide sequence can often be shared between two genes and in some...
3.
Lando D, Ma X, Cao Y, Jartseva A, Stevens T, Boucher W, et al.
Mol Cell
. 2024 Mar;
84(8):1406-1421.e8.
PMID: 38490199
Enhancers bind transcription factors, chromatin regulators, and non-coding transcripts to modulate the expression of target genes. Here, we report 3D genome structures of single mouse ES cells as they are...
4.
Rengifo Rojas C, Cercy J, Perillous S, Gonthier-Gueret C, Montibus B, Maupetit-Mehouas S, et al.
HGG Adv
. 2024 Feb;
5(2):100271.
PMID: 38297831
It is only partially understood how constitutive allelic methylation at imprinting control regions (ICRs) interacts with other regulation levels to drive timely parental allele-specific expression along large imprinted domains. The...
5.
Montibus B, Ragheb R, Diamanti E, Dunn S, Reynolds N, Hendrich B
Biol Open
. 2023 Dec;
13(1).
PMID: 38149716
As cells exit the pluripotent state and begin to commit to a specific lineage they must activate genes appropriate for that lineage while silencing genes associated with pluripotency and preventing...
6.
Boiteux E, Guichet P, Masliantsev K, Montibus B, Vaurs-Barriere C, Gonthier-Gueret C, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563134
Glioblastomas represent approximatively half of all gliomas and are the most deadly and aggressive form. Their therapeutic resistance and tumor relapse rely on a subpopulation of cells that are called...
7.
Cain J, Montibus B, Oakey R
Front Cell Dev Biol
. 2022 Feb;
10:832348.
PMID: 35223855
The mammalian genome is depleted in CG dinucleotides, except at protected regions where they cluster as CpG islands (CGIs). CGIs are gene regulatory hubs and serve as transcription initiation sites...
8.
Contreras Castillo S, Montibus B, Rocha A, Duke W, von Meyenn F, McLornan D, et al.
Genome Res
. 2021 Jul;
31(8):1381-1394.
PMID: 34244229
Hydroxycarbamide (HC, hydroxyurea) is a cytoreductive drug inducing cell cycle blockade. However, emerging evidence suggests that HC plays a role in the modulation of transcription through the activity of transcription...
9.
Prickett A, Montibus B, Barkas N, Amante S, Franco M, Cowley M, et al.
Front Cell Dev Biol
. 2021 Jul;
9:676543.
PMID: 34239874
Dopa decarboxylase (DDC) synthesizes serotonin in the developing mouse heart where it is encoded by , a tissue-specific paternally expressed imprinted gene. shares an imprinting control region (ICR) with the...
10.
Amante S, Montibus B, Cowley M, Barkas N, Setiadi J, Saadeh H, et al.
Nucleic Acids Res
. 2020 Jul;
48(15):8349-8359.
PMID: 32621610
Alternative splicing (AS) and alternative polyadenylation (APA) generate diverse transcripts in mammalian genomes during development and differentiation. Epigenetic marks such as trimethylation of histone H3 lysine 36 (H3K36me3) and DNA...