Bernice E Morrow
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Explore the profile of Bernice E Morrow including associated specialties, affiliations and a list of published articles.
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90
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Recent Articles
1.
Ferrena A, Zheng X, Jackson K, Hoang B, Morrow B, Zheng D
NAR Genom Bioinform
. 2024 Sep;
6(4):lqae134.
PMID: 39345754
Single-cell transcriptomics profiling has increasingly been used to evaluate cross-group (or condition) differences in cell population and cell-type gene expression. This often leads to large datasets with complex experimental designs...
2.
Racedo S, Liu Y, Shi L, Zheng D, Morrow B
Dev Biol
. 2023 Dec;
506:72-84.
PMID: 38110169
The DGCR8 gene, encoding a critical miRNA processing protein, maps within the hemizygous region in patients with 22q11.2 deletion syndrome. Most patients have malformations of the cardiac outflow tract that...
3.
Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, et al.
J Am Heart Assoc
. 2023 Sep;
12(18):e029683.
PMID: 37702066
Background Endocardial cells are a major progenitor population that gives rise to heart valves through endocardial cushion formation by endocardial to mesenchymal transformation and the subsequent endocardial cushion remodeling. Genetic...
4.
Shi L, Song H, Zhou B, Morrow B
bioRxiv
. 2023 Jul;
PMID: 37503032
Rationale: Ubiquitously expressed cytoplasmic adaptors CRK and CRKL mediate multiple signaling pathways in mammalian embryogenesis. They are also associated with cardiovascular defects occurring in Miller-Dieker syndrome and 22q11.2 deletion syndrome,...
5.
Zhao Y, Wang Y, Shi L, McDonald-McGinn D, Crowley T, McGinn D, et al.
NPJ Genom Med
. 2023 Jul;
8(1):17.
PMID: 37463940
Congenital heart disease (CHD) affecting the conotruncal region of the heart, occurs in 40-50% of patients with 22q11.2 deletion syndrome (22q11.2DS). This syndrome is a rare disorder with relative genetic...
6.
Bera B, Thompson T, Sosa E, Nomaru H, Reynolds D, Dubin R, et al.
Epigenetics Chromatin
. 2023 Apr;
16(1):14.
PMID: 37118773
Background: Single-cell technologies to analyze transcription and chromatin structure have been widely used in many research areas to reveal the functions and molecular properties of cells at single-cell resolution. Sample...
7.
De Bono C, Liu Y, Ferrena A, Valentine A, Zheng D, Morrow B
Nat Commun
. 2023 Mar;
14(1):1551.
PMID: 36941249
Disruption of cardiac neural crest cells (CNCCs) results in congenital heart disease, yet we do not understand the cell fate dynamics as these cells differentiate to vascular smooth muscle cells....
8.
Lin J, Zhao Y, Jabalameli M, Nguyen N, Mitra J, Swillen A, et al.
Mol Psychiatry
. 2023 Mar;
28(5):2071-2080.
PMID: 36869225
22q11.2 deletion is one of the strongest known genetic risk factors for schizophrenia. Recent whole-genome sequencing of schizophrenia cases and controls with this deletion provided an unprecedented opportunity to identify...
9.
Song H, Morrow B
Dev Biol
. 2022 Dec;
494:71-84.
PMID: 36521641
The morphogenesis of the otic vesicle (OV) to form inner ear organs serves as an excellent model system to understand cell fate acquisition on a single cell level. Tbx2 and...
10.
McGinn D, Crowley T, Heung T, Tran O, Moss E, Zackai E, et al.
Genes (Basel)
. 2022 Oct;
13(10).
PMID: 36292685
Learning and intellectual disabilities are hallmark features of 22q11.2 deletion syndrome. Data are limited, however, regarding influences on full-scale IQ (FSIQ). Here, we investigated possible 22q11.2 deletion parent-of-origin effects. In...