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Bernard Lakowski

Explore the profile of Bernard Lakowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 111
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Recent Articles
1.
Alvares S, Mayberry G, Joyner E, Lakowski B, Ahmed S
Aging Cell . 2013 Oct; 13(2):245-53. PMID: 24134677
Homeostasis of postmitotic and proliferating cells is maintained by pathways that repress stress. We found that the Caenorhabditis elegans histone 3 lysine 4 (H3K4) demethylases RBR-2 and SPR-5 promoted postmitotic...
2.
Verghese E, Schocken J, Jacob S, Wimer A, Royce R, Nesmith J, et al.
Dev Biol . 2011 Jul; 356(2):516-28. PMID: 21718694
The development of the C. elegans uterus provides a model for understanding the regulatory pathways that control organogenesis. In C. elegans, the ventral uterus develops through coordinated signaling between the...
3.
Gontijo A, Aubert S, Roelens I, Lakowski B
BMC Genet . 2009 Mar; 10:14. PMID: 19302704
Background: Presenilin proteins are part of a complex of proteins that can cleave many type I transmembrane proteins, including Notch Receptors and the Amyloid Precursor Protein, in the middle of...
4.
Lakowski B, Roelens I, Jacob S
J Mol Neurosci . 2006 Nov; 29(3):227-39. PMID: 17085781
The mammalian CoREST ([co]repressor for element-1-silencing transcription factor) complex was first identified associated with the repressor for element-1 silencing transcription factor (REST)/neuronal restrictive silencing factor. The CoREST complex is a...
5.
Lakowski B, Eimer S, Gobel C, Bottcher A, Wagler B, Baumeister R
Development . 2003 Apr; 130(10):2117-28. PMID: 12668626
Mutations in presenilin genes are associated with familial Alzheimer's disease in humans and affect LIN-12/Notch signaling in all organisms tested so far. Loss of sel-12 presenilin activity in Caenorhabditis elegans...