Bernard Coulie
Overview
Explore the profile of Bernard Coulie including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
463
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0
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Recent Articles
1.
Caluwaerts S, Vandenbroucke K, Steidler L, Neirynck S, Vanhoenacker P, Corveleyn S, et al.
Oral Oncol
. 2010 Jun;
46(7):564-70.
PMID: 20542722
Non-clinical studies, focusing on the pharmacodynamics (PD), pharmacokinetics (PK) and safety pharmacology of genetically modified Lactococcus lactis (L. lactis) bacteria, engineered to secrete human Trefoil Factor 1 (hTFF1), were performed...
2.
Steidler L, Rottiers P, Coulie B
Ann N Y Acad Sci
. 2010 Jan;
1182:135-45.
PMID: 20074282
Interleukin-10 (IL-10) is central in immune downregulation, but so far its use in inflammatory diseases remains cumbersome. For treatment of inflammatory bowel disease, adequate amounts of IL-10 must reach the...
3.
Aerssens J, Camilleri M, Talloen W, Thielemans L, Gohlmann H, Van den Wyngaert I, et al.
Clin Gastroenterol Hepatol
. 2008 Feb;
6(2):194-205.
PMID: 18237869
Background & Aims: Irritable bowel syndrome (IBS) has been associated with mucosal dysfunction, mild inflammation, and altered colonic bacteria. We used microarray expression profiling of sigmoid colon mucosa to assess...
4.
Thielemans L, Peeters P, Jonckheere H, Luyten W, De Hoogt R, Coulie B, et al.
J Recept Signal Transduct Res
. 2007 Sep;
27(4):309-22.
PMID: 17885924
The interaction of ghrelin, a 28-residue acylated peptide, with the growth hormone secretagogue receptor 1a (GHS-R1a) has been studied mostly in cells expressing a recombinant GHS-R1a. As awareness is growing...
5.
Aerssens J, Hillsley K, Peeters P, De Hoogt R, Stanisz A, Lin J, et al.
Gastroenterology
. 2007 Apr;
132(4):1375-87.
PMID: 17408648
Background & Aims: Visceral hypersensitivity, a hallmark of irritable bowel syndrome, is generally considered to be mechanosensitive in nature and mediated via spinal afferents. Both stress and inflammation are implicated...
6.
Camilleri M, Andrews C, Bharucha A, Carlson P, Ferber I, Stephens D, et al.
Gastroenterology
. 2007 Jan;
132(1):17-25.
PMID: 17241856
Background & Aims: The pathophysiology of irritable bowel syndrome (IBS) remains enigmatic; abnormalities in serotonin metabolism have been implicated. Two proteins that influence the function of serotonin and serotonergic receptors...
7.
Moechars D, Depoortere I, Moreaux B, De Smet B, Goris I, Hoskens L, et al.
Gastroenterology
. 2006 Oct;
131(4):1131-41.
PMID: 17030183
Background & Aims: The G-protein-coupled receptor GPR39 is a member of a family that includes the receptors for ghrelin and motilin. Recently the peptide obestatin was identified as a natural...
8.
Hillsley K, Lin J, Stanisz A, Grundy D, Aerssens J, Peeters P, et al.
J Physiol
. 2006 Jul;
576(Pt 1):257-67.
PMID: 16857712
Tetrodotoxin-resistant (TTX-R) sodium currents have been proposed to underlie sensory neuronal hyperexcitability in acute inflammatory models, but their role in chronic models is unknown. Since no pharmacological tools to separate...
9.
Cuomo R, Vandaele P, Coulie B, Peeters T, Depoortere I, Janssens J, et al.
Am J Gastroenterol
. 2006 Apr;
101(4):804-11.
PMID: 16635226
Background: Motilin agonists are strong gastroprokinetics, but their impact on symptoms in delayed gastric emptying has been disappointing. It has been speculated that it is due to the contractile effect...
10.
Peeters P, Aerssens J, De Hoogt R, Stanisz A, Gohlmann H, Hillsley K, et al.
Physiol Genomics
. 2005 Nov;
24(3):252-63.
PMID: 16303873
Vagal afferent neurons are thought to convey primarily physiological information, whereas spinal afferents transmit noxious signals from the viscera to the central nervous system. To elucidate molecular identities for these...