Bernadett Bacsa
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Explore the profile of Bernadett Bacsa including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
149
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Recent Articles
1.
Ray S, McCall J, Tian J, Jeon J, Douglas A, Tyler K, et al.
Sci Adv
. 2025 Jan;
11(3):eabm9843.
PMID: 39813349
Arthritis leads to bone erosion due to an imbalance between osteoclast and osteoblast function. Our prior investigations revealed that the Ca-selective ion channel, Orai1, is critical for osteoclast maturation. Here,...
2.
Bacsa B, Hopl V, Derler I
Cells
. 2024 Mar;
13(6.
PMID: 38534312
Many essential biological processes are triggered by the proximity of molecules. Meanwhile, diverse approaches in synthetic biology, such as new biological parts or engineered cells, have opened up avenues to...
3.
Bellini C, Vergara E, Bencs F, Fodor K, Bosze S, Krivic D, et al.
Bioconjug Chem
. 2023 Aug;
34(10):1738-1753.
PMID: 37606258
The complex immunopathology of() is one of the main challenges in developing a novel vaccine against this pathogen, particularly regarding eliciting protection against both active and latent stages. Multistage vaccines,...
4.
Bacsa B, Graziani A, Krivic D, Wiedner P, Malli R, Rauter T, et al.
Front Immunol
. 2021 Jan;
11:613194.
PMID: 33391284
Canonical transient receptor potential (TRPC) channels are considered as elements of the immune cell Ca handling machinery. We therefore hypothesized that TRPC photopharmacology may enable uniquely specific modulation of immune...
5.
Bacsa B, Tiapko O, Stockner T, Groschner K
Curr Opin Physiol
. 2020 Nov;
17:25-33.
PMID: 33210055
The transient receptor potential (TRP) superfamily of plasma membrane cation channels has been recognized as a signaling hub in highly diverse settings of human physiopathology. In the past three decades...
6.
Shrestha N, Bacsa B, Ong H, Scheruebel S, Bischof H, Malli R, et al.
PLoS Biol
. 2020 Apr;
18(4):e3000700.
PMID: 32330125
Trimeric intracellular cation (TRIC) channels have been proposed to modulate Ca2+ release from the endoplasmic reticulum (ER) and determine oscillatory Ca2+ signals. Here, we report that TRIC-A-mediated amplitude and frequency...
7.
Graziani A, Bacsa B, Krivic D, Wiedner P, Curcic S, Schindl R, et al.
Cells
. 2020 Mar;
9(3).
PMID: 32120825
Canonical transient receptor potential (TRPC) channels were identified as key players in maladaptive remodeling, with nuclear factor of activated T-cells (NFAT) transcription factors serving as downstream targets of TRPC-triggered Ca...
8.
Horvati K, Bacsa B, Mlinko T, Szabo N, Hudecz F, Zsila F, et al.
Amino Acids
. 2017 Mar;
49(6):1053-1067.
PMID: 28314993
Cationic peptides proved fundamental importance as pharmaceutical agents and/or drug carrier moieties functioning in cellular processes. The comparison of the in vitro activity of these peptides is an experimental challenge...
9.
Tiapko O, Bacsa B, Guedes de la Cruz G, Glasnov T, Groschner K
Sci China Life Sci
. 2016 Jul;
59(8):802-10.
PMID: 27430887
Photouncaging of second messengers has been successfully employed to gain mechanistic insight of cellular signaling pathways. One of the most enigmatic processes of ion channel regulation is lipid recognition and...
10.
Moehle K, Kocherla H, Bacsa B, Jurt S, Zerbe K, Robinson J, et al.
Biochemistry
. 2016 May;
55(21):2936-43.
PMID: 27166502
LptE is an outer membrane (OM) lipoprotein found in Gram-negative bacteria, where it forms a complex with the β-barrel lipopolysaccharide (LPS) transporter LptD. The LptD/E complex plays a key role...