Benoit Laurent
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Explore the profile of Benoit Laurent including associated specialties, affiliations and a list of published articles.
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44
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1346
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Recent Articles
1.
Najia M, Jha D, Zhang C, Laurent B, Kubaczka C, Markel A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975048
Genes involved in the regulation of chromatin structure are frequently disrupted in cancer, contributing to an aberrant transcriptome and phenotypic plasticity. Yet, therapeutics targeting mutant forms of chromatin-modifying enzymes have...
2.
Porter R, An S, Gavilan M, Nagai M, Murata-Nakamura Y, Zhou B, et al.
Cell Rep
. 2025 Jan;
44(1):115213.
PMID: 39817906
Chromatin regulatory proteins are expressed broadly and assumed to exert the same intrinsic function across cell types. Here, we report that 14 chromatin regulators undergo evolutionary-conserved neuron-specific splicing events involving...
3.
Audoux T, Laurent B, Chevaillier S, Desboeufs K
Sci Total Environ
. 2025 Jan;
962():178308.
PMID: 39808896
Understanding the solubility dynamics of elements during wet deposition is crucial for assessing their environmental impacts. In this study, we investigated the solubility behaviour of various elements originating from natural...
4.
Dionne O, Sabatie S, Fortin F, Corbin F, Laurent B
Front Cell Dev Biol
. 2024 Dec;
12:1489190.
PMID: 39650724
Human induced pluripotent stem cells (iPSCs) are a valuable tool for studying human development and diseases. iPSCs can be generated by reprogramming from any somatic cells, however establishing primary cell...
5.
Andriambelo B, Vachon A, Dansereau M, Laurent B, Plourde M
Prostaglandins Leukot Essent Fatty Acids
. 2024 Dec;
204:102661.
PMID: 39642444
Background: Several mechanisms have been proposed for the brain uptake of omega-3 fatty acids (n-3), including passive diffusion of the unesterified form and the use of Mfsd2a transporter for the...
6.
Alami M, Boumezough K, Zerif E, Zoubdane N, Khalil A, Bunt T, et al.
Nutrients
. 2024 Nov;
16(21).
PMID: 39519499
Background: Oxidative stress and chronic inflammation, at both the systemic and the central level, are critical early events in atherosclerosis and Alzheimer's disease (AD). Purpose: To investigate the oxidative stress-,...
7.
Dionne O, Sabatie S, Laurent B
Brain
. 2024 Sep;
148(1):12-26.
PMID: 39222411
Neurodevelopmental disorders (NDD) encompass a range of conditions marked by abnormal brain development in conjunction with impaired cognitive, emotional and behavioural functions. Transgenic animal models, mainly rodents, traditionally served as...
8.
Petit E, Bavykina V, Thibault M, Bilodeau A, Choiniere W, Brosseau J, et al.
J Mech Behav Biomed Mater
. 2024 Aug;
159:106709.
PMID: 39216337
The development of biomaterials such as synthetic scaffolds for peripheral nerve regeneration requires a precise knowledge of the mechanical properties of the nerve in physiological-like conditions. Mechanical properties (Young's modulus,...
9.
Porter R, Nagai M, An S, Gavilan M, Murata-Nakamura Y, Bonefas K, et al.
bioRxiv
. 2023 Oct;
PMID: 37904995
How cell-type-specific chromatin landscapes emerge and progress during metazoan ontogenesis remains an important question. Transcription factors are expressed in a cell-type-specific manner and recruit chromatin-regulatory machinery to specific genomic loci....
10.
Fulop T, Ramassamy C, Levesque S, Frost E, Laurent B, Lacombe G, et al.
Expert Rev Neurother
. 2023 Aug;
23(9):775-790.
PMID: 37551672
Introduction: Clinically, Alzheimer's disease (AD) is a syndrome with a spectrum of various cognitive disorders. There is a complete dissociation between the pathology and the clinical presentation. Therefore, we need...