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Benjamin T K Yuen

Explore the profile of Benjamin T K Yuen including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 176
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Recent Articles
1.
Smith J, Yuen B, Purtha W, Balolong J, Phipps J, Crawford F, et al.
Proc Natl Acad Sci U S A . 2024 May; 121(20):e2320268121. PMID: 38709934
Insulin is a central autoantigen in the pathogenesis of T1D, and thymic epithelial cell expression of insulin under the control of the Autoimmune Regulator () is thought to be a...
2.
Martinez-Cerdeno V, Barrilleaux B, McDonough A, Ariza J, Yuen B, Somanath P, et al.
Stem Cells Dev . 2017 Jul; 26(19):1409-1423. PMID: 28693365
Human pluripotent stem cells (hPSC) have great clinical potential through the use of their differentiated progeny, a population in which there is some concern over risks of tumorigenicity or other...
3.
Yuen B, Bush K, Barrilleaux B, Cotterman R, Knoepfler P
Development . 2014 Aug; 141(18):3483-94. PMID: 25142466
The histone variant H3.3 is involved in diverse biological processes, including development, transcriptional memory and transcriptional reprogramming, as well as diseases, including most notably malignant brain tumors. Recently, we developed...
4.
Yuen B, Knoepfler P
Cancer Cell . 2013 Nov; 24(5):567-74. PMID: 24229707
A host of cancer types exhibit aberrant histone modifications. Recently, distinct and recurrent mutations in a specific histone variant, histone H3.3, have been implicated in a high proportion of malignant...
5.
Meissen J, Yuen B, Kind T, Riggs J, Barupal D, Knoepfler P, et al.
PLoS One . 2012 Oct; 7(10):e46770. PMID: 23077522
Induced pluripotent stem cells are different from embryonic stem cells as shown by epigenetic and genomics analyses. Depending on cell types and culture conditions, such genetic alterations can lead to...