Benjamin T Jackson
Overview
Explore the profile of Benjamin T Jackson including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
337
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Recent Articles
1.
Paras K, Brunner J, Boyer J, Montero A, Jackson B, Chakraborty S, et al.
bioRxiv
. 2025 Jan;
PMID: 39868247
PAX3-FOXO1, an oncogenic transcription factor, drives a particularly aggressive subtype of rhabdomyosarcoma (RMS) by enforcing gene expression programs that support malignant cell states. Here we show that PAX3-FOXO1 RMS cells...
2.
Millman S, Chaves-Perez A, Janaki-Raman S, Ho Y, Morris Iv J, Narendra V, et al.
Blood
. 2025 Jan;
PMID: 39791576
Perturbations in intermediary metabolism contribute to the pathogenesis of acute myeloid leukemia (AML) and can produce therapeutically actionable dependencies. Here, we probed whether alpha-ketoglutarate (aKG) metabolism represents a specific vulnerability...
3.
Jackson B, Finley L
Cell Stem Cell
. 2024 Feb;
31(2):161-180.
PMID: 38306993
Stem cells perform many different functions, each of which requires specific metabolic adaptations. Over the past decades, studies of pluripotent and tissue stem cells have uncovered a range of metabolic...
4.
Todorova P, Jackson B, Garg V, Paras K, Brunner J, Bridgeman A, et al.
Nat Metab
. 2024 Jan;
6(1):127-140.
PMID: 38172382
Mammalian preimplantation development is associated with marked metabolic robustness, and embryos can develop under a wide variety of nutrient conditions, including even the complete absence of soluble amino acids. Here...
5.
6.
Arnold P, Jackson B, Paras K, Brunner J, Hart M, Newsom O, et al.
Nature
. 2022 Mar;
603(7901):477-481.
PMID: 35264789
The tricarboxylic acid (TCA) cycle is a central hub of cellular metabolism, oxidizing nutrients to generate reducing equivalents for energy production and critical metabolites for biosynthetic reactions. Despite the importance...
7.
Dey S, Filonov G, Olarerin-George A, Jackson B, Finley L, Jaffrey S
Nat Chem Biol
. 2022 Jan;
18(2):236.
PMID: 35064247
No abstract available.
8.
Dey S, Filonov G, Olarerin-George A, Jackson B, Finley L, Jaffrey S
Nat Chem Biol
. 2021 Dec;
18(2):180-190.
PMID: 34937909
Fluorogenic RNA aptamers are used to genetically encode fluorescent RNA and to construct RNA-based metabolite sensors. Unlike naturally occurring aptamers that efficiently fold and undergo metabolite-induced conformational changes, fluorogenic aptamers...
9.
Adams N, Geary C, Santosa E, Lumaquin D, Le Luduec J, Sottile R, et al.
Immunity
. 2019 May;
50(6):1381-1390.e5.
PMID: 31103381
The process of affinity maturation, whereby T and B cells bearing antigen receptors with optimal affinity to the relevant antigen undergo preferential expansion, is a key feature of adaptive immunity....
10.
Delas M, Jackson B, Kovacevic T, Vangelisti S, Munera Maravilla E, Wild S, et al.
Cell Rep
. 2019 Apr;
27(3):719-729.e6.
PMID: 30995471
Long non-coding RNAs (lncRNAs) show patterns of tissue- and cell type-specific expression that are very similar to those of protein coding genes and consequently have the potential to control stem...