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Benjamin Shykind

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Citations 167
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Recent Articles
1.
Bashkirova E, Klimpert N, Monahan K, Campbell C, Osinski J, Tan L, et al.
bioRxiv . 2023 Mar; PMID: 36993168
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in a probabilistic, yet stereotypic fashion. Here, we...
2.
Abdus-Saboor I, Fleischmann A, Shykind B
Transcription . 2015 Mar; 5(3):e28978. PMID: 25764336
Odorant receptor (OR) gene choice is a paradigmatic example of stochastic regulation in which olfactory neurons choose one OR from > 1,000 possibilities. Recent biochemical, mathematical, and in vivo findings...
3.
Fleischmann A, Abdus-Saboor I, Sayed A, Shykind B
PLoS Biol . 2013 May; 11(5):e1001568. PMID: 23700388
The odorant receptor (OR) genes constitute the largest mammalian gene family and are expressed in a monogenic and monoallelic fashion, through an unknown mechanism that likely exploits positive and negative...
4.
Zhang H, Shykind B, Sun T
Front Neurosci . 2013 Jan; 6:196. PMID: 23335878
Neurogenesis in the nervous system is regulated by both protein coding genes and non-coding RNA molecules. microRNAs (miRNAs) are endogenous small non-coding RNAs and usually negatively regulate gene expression by...
5.
Yang X, Ai W, Asfaha S, Bhagat G, Friedman R, Jin G, et al.
Nat Med . 2010 Dec; 17(1):87-95. PMID: 21170045
Histidine decarboxylase (HDC), the unique enzyme responsible for histamine generation, is highly expressed in myeloid cells, but its function in these cells is poorly understood. Here we show that Hdc-knockout...