Benjamin Rowlinson
Overview
Explore the profile of Benjamin Rowlinson including associated specialties, affiliations and a list of published articles.
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6
Citations
46
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Recent Articles
1.
Dewison K, Rowlinson B, Machin J, Crossley J, Thacker D, Wilkinson M, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(34):e2315006121.
PMID: 39133842
Amyloid formation by α-synuclein (αSyn) occurs in Parkinson's disease, multiple system atrophy, and dementia with Lewy bodies. Deciphering the residues that regulate αSyn amyloid fibril formation will not only provide...
2.
Tang Q, Petchey M, Rowlinson B, Burden T, Fairlamb I, Grogan G
ACS Catal
. 2024 Jan;
14(2):1021-1029.
PMID: 38269041
The synthesis of amide bonds is one of the most frequently performed reactions in pharmaceutical synthesis, but the requirement for stoichiometric quantities of coupling agents and activated substrates in established...
3.
Rowlinson B, Crublet E, Kerfah R, Plevin M
Biochem Soc Trans
. 2022 Nov;
50(6):1555-1567.
PMID: 36382942
The study of protein structure, dynamics and function by NMR spectroscopy commonly requires samples that have been enriched ('labelled') with the stable isotopes 13C and/or 15N. The standard approach is...
4.
Petchey M, Rowlinson B, Lloyd R, Fairlamb I, Grogan G
ACS Catal
. 2020 Apr;
10(8):4659-4663.
PMID: 32337091
The biocatalytic synthesis of amides from carboxylic acids and primary amines in aqueous media can be achieved using the ATP-dependent amide bond synthetase McbA, via an adenylate intermediate, using only...
5.
Klenk J, Fischer M, Dubiel P, Sharma M, Rowlinson B, Grogan G, et al.
J Biochem
. 2019 Feb;
166(1):51-66.
PMID: 30759214
Cytochrome P450 monooxygenases (P450s) play crucial roles in the cell metabolism and provide an unsurpassed diversity of catalysed reactions. Here, we report the identification and biochemical characterization of two P450s...
6.
Petchey M, Cuetos A, Rowlinson B, Dannevald S, Frese A, Sutton P, et al.
Angew Chem Int Ed Engl
. 2018 Jul;
57(36):11584-11588.
PMID: 30035356
Amide bond formation is one of the most important reactions in pharmaceutical synthetic chemistry. The development of sustainable methods for amide bond formation, including those that are catalyzed by enzymes,...