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Benjamin M Janus

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Recent Articles
1.
Janus B, Wang R, Cleveland 4th T, Metcalf M, Lemmer A, van Dyk N, et al.
J Virol . 2024 Jun; 98(7):e0015524. PMID: 38832790
Importance: Marburg viruses were the first filoviruses characterized to emerge in humans in 1967 and cause severe hemorrhagic fever with average case fatality rates of ~50%. Although mAb countermeasures have...
2.
Williams W, Alam S, Ofek G, Erdmann N, Montefiori D, Seaman M, et al.
Cell . 2024 May; 187(12):2919-2934.e20. PMID: 38761800
A critical roadblock to HIV vaccine development is the inability to induce B cell lineages of broadly neutralizing antibodies (bnAbs) in humans. In people living with HIV-1, bnAbs take years...
3.
Metcalf M, Janus B, Yin R, Wang R, Guest J, Pozharski E, et al.
Nat Commun . 2023 Jul; 14(1):3980. PMID: 37407593
Hepatitis C virus (HCV) is a major global health burden as the leading causative agent of chronic liver disease and hepatocellular carcinoma. While the main antigenic target for HCV-neutralizing antibodies...
4.
Romanyuk A, Wang R, Marin A, Janus B, Felner E, Xia D, et al.
J Funct Biomater . 2023 Jan; 14(1). PMID: 36662063
Ebolavirus (EBOV) infection in humans is a severe and often fatal disease, which demands effective interventional strategies for its prevention and treatment. The available vaccines, which are authorized under exceptional...
5.
Janus B, van Dyk N, Zhao X, Howell K, Soto C, Aman M, et al.
Nat Commun . 2018 Sep; 9(1):3934. PMID: 30258051
The severity of the 2014-2016 ebolavirus outbreak in West Africa expedited clinical development of therapeutics and vaccines though the countermeasures on hand were largely monospecific and lacked efficacy against other...