Benjamin M Gaston
Overview
Explore the profile of Benjamin M Gaston including associated specialties, affiliations and a list of published articles.
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39
Citations
1565
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Recent Articles
1.
Saunders J, Daniels I, Edwards T, Relich R, Zhao Y, Smith L, et al.
ERJ Open Res
. 2023 Jul;
9(4).
PMID: 37465558
Background: Respiratory syncytial virus (RSV) is a leading cause of respiratory distress and hospitalisation in the paediatric population. Low airway surface pH impairs antimicrobial host defence and worsens airway inflammation....
2.
Li X, Li H, Christenson S, Castro M, Denlinger L, Erzurum S, et al.
J Asthma
. 2023 Mar;
60(10):1824-1835.
PMID: 36946148
Objective: Genome-wide association studies (GWASs) have identified single nucleotide polymorphisms (SNPs) in chr11p15.5 region associated with asthma and idiopathic interstitial pneumonias (IIPs). We sought to identify functional genes for asthma...
3.
Israel E, Denlinger L, Bacharier L, LaVange L, Moore W, Peters M, et al.
J Allergy Clin Immunol
. 2021 Mar;
147(5):1594-1601.
PMID: 33667479
Severe asthma accounts for almost half the cost associated with asthma. Severe asthma is driven by heterogeneous molecular mechanisms. Conventional clinical trial design often lacks the power and efficiency to...
4.
Ivanova A, Israel E, LaVange L, Peters M, Denlinger L, Moore W, et al.
J Biopharm Stat
. 2020 Sep;
30(6):1026-1037.
PMID: 32941098
The Precision Interventions for Severe and/or Exacerbation-prone Asthma (PrecISE) study is an adaptive platform trial designed to investigate novel interventions to severe asthma. The study is conducted under a master...
5.
Hannah W, Truty R, Gonzales V, Kithcart G, Ouyang K, Zeman M, et al.
J Pediatr
. 2019 Oct;
215:172-177.e2.
PMID: 31610925
Objective: To evaluate whether cystic fibrosis transmembrane conductance regulator (CFTR) variants are more common among individuals tested for primary ciliary dyskinesia (PCD) compared with controls. Study Design: Data were studied...
6.
Fitzpatrick A, Szefler S, Mauger D, Phillips B, Denlinger L, Moore W, et al.
J Allergy Clin Immunol
. 2019 Oct;
145(1):127-139.
PMID: 31604088
Background: Tools for quantification of asthma severity are limited. Objective: We sought to develop a continuous measure of asthma severity, the Asthma Severity Scoring System (ASSESS), for adolescents and adults,...
7.
Ash S, Sanchez-Ferrero G, Schiebler M, Rahaghi F, Rai A, Come C, et al.
Chest
. 2019 Sep;
157(2):258-267.
PMID: 31521672
Background: Relative enlargement of the pulmonary artery (PA) on chest CT imaging is associated with respiratory exacerbations in patients with COPD or cystic fibrosis. We sought to determine whether similar...
8.
Coverstone A, Bacharier L, Wilson B, Fitzpatrick A, Teague W, Phipatanakul W, et al.
Pediatr Pulmonol
. 2019 Aug;
54(11):1694-1703.
PMID: 31424170
Background: Our objective was to determine those characteristics associated with reversibility of airflow obstruction and response to maximal bronchodilation in children with severe asthma through the Severe Asthma Research Program...
9.
Ross K, Teague W, Gaston B
Clin Chest Med
. 2019 Jan;
40(1):125-147.
PMID: 30691707
Asthma is a heterogeneous developmental disorder influenced by complex interactions between genetic susceptibility and exposures. Wheezing in infancy and early childhood is highly prevalent, with a substantial minority of children...
10.
Wu W, Bang S, Bleecker E, Castro M, Denlinger L, Erzurum S, et al.
Am J Respir Crit Care Med
. 2019 Jan;
199(11):1358-1367.
PMID: 30682261
Corticosteroids (CSs) are the most effective asthma therapy, but responses are heterogeneous and systemic CSs lead to long-term side effects. Therefore, an improved understanding of the contributing factors in CS...