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Benjamin K Johnson

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Articles 45
Citations 859
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Recent Articles
21.
Sandoval Y, Gunsolus I, Smith S, Sexter A, Thordsen S, Carlson M, et al.
Am J Med . 2019 Mar; 132(7):869-874. PMID: 30849383
Objective: Our objective was to examine the appropriateness of cardiac troponin (cTn) testing among patients with cTn increases. Methods: This is a planned secondary analysis of the Use of TROPonin...
22.
Capone S, Colombo A, Johnson B, Triche Jr T, Ramsingh G
Exp Hematol Oncol . 2019 Jan; 7:32. PMID: 30598855
Senescence, a state of permanent cell cycle arrest, can be induced by DNA damage. This process, which was initially described in fibroblasts, is now recognized to occur in stem cells....
23.
Wu Z, Senchuk M, Dues D, Johnson B, Cooper J, Lew L, et al.
BMC Biol . 2018 Dec; 16(1):147. PMID: 30563508
Background: The mitochondrial unfolded protein response (mitoUPR) is a stress response pathway activated by disruption of proteostasis in the mitochondria. This pathway has been proposed to influence lifespan, with studies...
24.
Rosenbaum J, Johnson B, Deane A
Digit Health . 2018 Jun; 4:2055207618770765. PMID: 29942630
Improving health literacy is increasingly seen as a solution to health problems and inequalities. This study assesses how one of the more recent measures of health literacy, the Health Literacy...
25.
Senchuk M, Dues D, Schaar C, Johnson B, Madaj Z, Bowman M, et al.
PLoS Genet . 2018 Mar; 14(3):e1007268. PMID: 29522556
Mild deficits in mitochondrial function have been shown to increase lifespan in multiple species including worms, flies and mice. Here, we study three C. elegans mitochondrial mutants (clk-1, isp-1 and...
26.
Coulson G, Johnson B, Zheng H, Colvin C, Fillinger R, Haiderer E, et al.
Cell Chem Biol . 2017 Aug; 24(8):993-1004.e4. PMID: 28781126
Mycobacterium tuberculosis (Mtb) must sense and adapt to immune pressures such as acidic pH during pathogenesis. The goal of this study was to isolate compounds that inhibit acidic pH resistance,...
27.
Jeon A, Obregon-Henao A, Ackart D, Podell B, Belardinelli J, Jackson M, et al.
PLoS One . 2017 Jul; 12(7):e0180925. PMID: 28749949
There is an urgent need to develop new drug treatment strategies to control the global spread of drug-sensitive and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis). The ß-lactam class of antibiotics is...
28.
Sandoval Y, Smith S, Sexter A, Thordsen S, Bruen C, Carlson M, et al.
Am J Med . 2017 Jul; 130(12):1431-1439.e4. PMID: 28739197
Background: Studies addressing patients with type 2 myocardial infarction and myocardial injury, including the impact of using high-sensitivity (hs) cardiac troponin (cTn) assays on their incidence are needed. Methods: Ours...
29.
Sandoval Y, Smith S, Thordsen S, Bruen C, Carlson M, Dodd K, et al.
Clin Chem . 2017 Jul; 63(10):1594-1604. PMID: 28701316
Background: We examined the diagnostic performance of high-sensitivity cardiac troponin I (hs-cTnI) vs contemporary cTnI with use of the 99th percentile alone and with a normal electrocardiogram (ECG) to rule...
30.
Dues D, Schaar C, Johnson B, Bowman M, Winn M, Senchuk M, et al.
Free Radic Biol Med . 2017 Apr; 108:362-373. PMID: 28392283
Mutations affecting components of the mitochondrial electron transport chain have been shown to increase lifespan in multiple species including the worm Caenorhabditis elegans. While it was originally proposed that decreased...