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Benjamin J Solomon

Explore the profile of Benjamin J Solomon including associated specialties, affiliations and a list of published articles. Areas
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Articles 107
Citations 11561
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Recent Articles
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Gautschi O, Park K, Solomon B, Tomasini P, Loong H, De Braud F, et al.
J Clin Oncol . 2025 Feb; :JCO2402076. PMID: 39983053
LIBRETTO-001 (ClinicalTrials.gov identifier: NCT03157128) is a registrational phase I/II, single-arm, open-label trial of selpercatinib in RET-dependent cancers. With 19 months of additional follow-up, we report the final efficacy and safety...
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Lee C, Liao B, Subramaniam S, Chiu C, Mersiades A, Ho C, et al.
JTO Clin Res Rep . 2025 Jan; 6(2):100771. PMID: 39877028
Introduction: -mutant NSCLC is associated with low mutation burden and low levels of PD-L1 expression. We conducted a phase 2 trial to determine the efficacy of durvalumab, tremelimumab, and platinum-pemetrexed...
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Ou S, Solomon B, Besse B, Bearz A, Lin C, Chiari R, et al.
J Thorac Oncol . 2024 Nov; PMID: 39581380
Introduction: Lorlatinib is a potent, brain-penetrant, third-generation inhibitor of anaplastic lymphoma kinase (ALK) and ROS1 tyrosine kinases with broad coverage of ALK resistance mutations. We present the overall survival (OS)...
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Cheung B, Mittra R, Murray J, Wang Q, Seneviratne J, Raipuria M, et al.
Commun Biol . 2024 Oct; 7(1):1322. PMID: 39402275
MYCN amplification predicts poor prognosis in childhood neuroblastoma. To identify MYCN oncogenic signal dependencies we performed N-ethyl-N-nitrosourea (ENU) mutagenesis on the germline of neuroblastoma-prone TH-MYCN transgenic mice to generate founders...
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Solomon B, Liu G, Felip E, Mok T, Soo R, Mazieres J, et al.
Future Oncol . 2024 Oct; 20(40):3377-3387. PMID: 39360949
What Is This Study About?: This is a summary of the results of an ongoing study called CROWN. In the CROWN study, researchers looked at the effects of two medicines...
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Itchins M, Liang S, Brown C, Barnes T, Marx G, Chin V, et al.
JTO Clin Res Rep . 2024 Sep; 5(9):100703. PMID: 39309618
Introduction: ALK-positive lung cancers represent a molecularly diverse disease. With drug exposure, driving selection pressure, and resistance pathways, disease relapse will emerge. There is compelling rationale to investigate novel treatment...
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Smith K, OHaire S, Markman B, Gan H, OByrne K, Millward M, et al.
JCO Precis Oncol . 2024 Aug; 8:e2300247. PMID: 39208376
Purpose: Despite increasing evidence of benefit supporting complex genomic sequencing (CGS) in personalizing cancer therapy, its widespread uptake remains limited. Methods: This mixed-methods, prospective cross-institutional demonstration study was designed to...
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Solomon B, Dagogo-Jack I, Lee S, Boyer M, Ramalingam S, Carcereny E, et al.
JTO Clin Res Rep . 2024 Jul; 5(7):100685. PMID: 39034968
Introduction: The JAVELIN Lung 101 phase 1b/2 trial evaluated avelumab (immune checkpoint inhibitor) combined with lorlatinib or crizotinib (tyrosine kinase inhibitors) in -positive or -negative advanced NSCLC, respectively. Methods: Starting...
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Felip E, Metro G, Soo R, Wolf J, Solomon B, Tan D, et al.
Eur J Cancer . 2024 Jul; 208:114182. PMID: 38986421
Purpose: This phase 1b/2 trial evaluated the efficacy and safety of capmatinib plus nazartinib in patients with advanced EGFR-mutated non-small cell lung cancer (NSCLC). Methods: In phase 1b, patients with...