Benjamin J Hindson
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Explore the profile of Benjamin J Hindson including associated specialties, affiliations and a list of published articles.
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21
Citations
5754
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0
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Recent Articles
1.
Zheng G, Terry J, Belgrader P, Ryvkin P, Bent Z, Wilson R, et al.
Nat Commun
. 2017 Jan;
8:14049.
PMID: 28091601
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3' mRNA counting of tens of thousands of single cells...
2.
Zheng G, Lau B, Schnall-Levin M, Jarosz M, Bell J, Hindson C, et al.
Nat Biotechnol
. 2016 Feb;
34(3):303-11.
PMID: 26829319
Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of genetic variation. We present a microfluidics-based, linked-read sequencing technology that can phase and haplotype germline and cancer...
3.
McDermott G, Do D, Litterst C, Maar D, Hindson C, Steenblock E, et al.
Anal Chem
. 2013 Nov;
85(23):11619-27.
PMID: 24180464
Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering all researchers with a tool that removes the substantial uncertainties associated with using the analogue...
4.
Hindson C, Chevillet J, Briggs H, Gallichotte E, Ruf I, Hindson B, et al.
Nat Methods
. 2013 Sep;
10(10):1003-5.
PMID: 23995387
Nanoliter-sized droplet technology paired with digital PCR (ddPCR) holds promise for highly precise, absolute nucleic acid quantification. Our comparison of microRNA quantification by ddPCR and real-time PCR revealed greater precision...
5.
Belgrader P, Tanner S, Regan J, Koehler R, Hindson B, Brown A
Clin Chem
. 2013 Jan;
59(6):991-4.
PMID: 23358413
Background: Human epidermal growth factor receptor 2 (HER2) testing is routinely performed by immunohistochemistry (IHC) and/or fluorescence in situ hybridization (FISH) analyses for all new cases of invasive breast carcinoma....
6.
Pinheiro L, Coleman V, Hindson C, Herrmann J, Hindson B, Bhat S, et al.
Anal Chem
. 2011 Nov;
84(2):1003-11.
PMID: 22122760
Droplet digital polymerase chain reaction (ddPCR) is a new technology that was recently commercialized to enable the precise quantification of target nucleic acids in a sample. ddPCR measures absolute quantities...
7.
Hindson B, Ness K, Masquelier D, Belgrader P, Heredia N, Makarewicz A, et al.
Anal Chem
. 2011 Nov;
83(22):8604-10.
PMID: 22035192
Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of scalable and practical technologies for digital PCR implementation has hampered the widespread adoption of this...
8.
Wilson W, Hindson B, OHearn E, Hall S, Tellgren-Roth C, Torres C, et al.
J Vet Diagn Invest
. 2009 Nov;
21(6):760-70.
PMID: 19901276
Bluetongue virus (BTV) causes disease in domestic and wild ruminants and results in significant economic loss. The closely related Epizootic hemorrhagic disease virus (EHDV) has been associated with bluetongue-like disease...
9.
Anastos N, Barnett N, Hindson B, Lenehan C, Lewis S
Talanta
. 2008 Oct;
64(1):130-4.
PMID: 18969577
The limits of detection (3s) for ascorbic acid were 5x10(-8)M with acidic potassium permanganate using both flow injection analysis (FIA) and sequential injection analysis (SIA) whereas the soluble manganese(IV) afforded...
10.
Regan J, Makarewicz A, Hindson B, Metz T, Gutierrez D, Corzett T, et al.
Anal Chem
. 2008 Sep;
80(19):7422-9.
PMID: 18763806
We have developed and field-tested a now operational civilian biodefense capability that continuously monitors the air in high-risk locations for biological threat agents. This stand-alone instrument, called the Autonomous Pathogen...