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Benjamin J Bythell

Explore the profile of Benjamin J Bythell including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 450
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Recent Articles
1.
Armbruster M, Grady S, Cho K, Patti G, Bythell B, Arnatt C, et al.
Anal Chem . 2024 Jul; 96(32):12937-12942. PMID: 39082755
Liquid chromatography-mass spectrometry (LC-MS) based metabolomics suffers from extended duty cycles and matrix-dependent quantitation. Chemical tags with 96 unique masses are reported, which alleviate the metabolomic workflow bottleneck and allow...
2.
Agongo J, Grady S, Cho K, Patti G, Bythell B, Arnatt C, et al.
Anal Chem . 2024 Jul; 96(29):11639-11643. PMID: 38976774
Discovery and identification of a new endogenous metabolite are typically hindered by requirements of large sample volumes and multistage purifications to guide synthesis of the standard. Presented here is a...
3.
Loncaric D, Movahedifar F, Radek Stocek J, Dracinsky M, Cvacka J, Guan S, et al.
Chem Sci . 2023 Sep; 14(35):9258-9266. PMID: 37712024
Cucurbit[7]uril (CB[7]) encapsulates adamantyl and trimethylsilyl substituents of positively charged guests in dimethyl sulfoxide (DMSO). Unlike in water or deuterium oxide, addition of a selection of alkali and alkali-earth cations...
4.
Mostafa M, Hayes M, Grinias J, Bythell B, Edwards J
J Am Soc Mass Spectrom . 2023 Apr; 34(6):995-1005. PMID: 37097105
Nanospraying supercritical fluids coupled to a mass spectrometer (nSF-MS) using a 90% supercritical fluid CO carrier (sCO) has shown an enhanced desolvation compared to traditional liquid eluents. Capillaries of 25,...
5.
Skelton E, Erasquin U, Sukul A, Zuercher A, White J, Bythell B, et al.
Inorg Chem . 2023 Feb; 62(8):3368-3380. PMID: 36795094
Most photodynamic therapeutics (PDTs) used in cancer treatment require oxygen to work efficiently to terminate cancer cells. These PDTs do not efficiently treat tumors in hypoxic conditions. Rh(III) polypyridyl complexes...
6.
Rabus J, Guan S, Schultz L, Abutokaikah M, Maitre P, Bythell B
J Am Soc Mass Spectrom . 2022 Aug; 33(9):1745-1752. PMID: 36018613
We recently provided mass spectrometric, H/D labeling, and computational evidence of pyranose to furanose -acetylated ion isomerization reactions that occurred prior to glycosidic bond cleavage in both O- and N-linked...
7.
Cimatu K, Ambagaspitiya T, Premadasa U, Adhikari N, Kruse A, Robertson E, et al.
J Colloid Interface Sci . 2022 Feb; 616:221-233. PMID: 35203035
Hypothesis: We hypothesize that varying the chemical structure of the monomeric unit in a polymer will affect the surface structure and interfacial molecular group orientations of the polymer film leveraging...
8.
Guan S, Bythell B
Phys Chem Chem Phys . 2021 Oct; 23(40):23256-23266. PMID: 34632474
Peptidoglycans are diverse co- and post-translational modifications of key importance in myriad biological processes. Mass spectrometry is employed to infer their biomolecular sequences and stereochemisties, but little is known about...
9.
Rabus J, Pellegrinelli R, Khodr A, Bythell B, Rizzo T, Carrascosa E
Phys Chem Chem Phys . 2021 Jun; 23(24):13714-13723. PMID: 34128027
We present cryogenic infrared spectra of sodiated β-cyclodextrin [β-CD + Na]+, a common cyclic oligosaccharide, and its main dissociation products upon collision-induced dissociation (CID). We characterize the parent ions using...
10.
Guan S, Bythell B
J Am Soc Mass Spectrom . 2021 Mar; 32(4):1020-1032. PMID: 33779179
Tandem mass spectrometry of electrospray ionized multiply charged peptide ions is commonly used to identify the sequence of peptide(s) and infer the identity of source protein(s). Doubly protonated peptide ions...