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Benjamin Herquel

Explore the profile of Benjamin Herquel including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 381
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Recent Articles
1.
Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska E, Peyronnet R, et al.
Nat Cell Biol . 2023 Feb; 25(4):626. PMID: 36849559
No abstract available.
2.
Pessoa Rodrigues C, Herman J, Herquel B, Keller Valsecchi C, Stehle T, Grun D, et al.
Sci Adv . 2020 Jul; 6(21):eaaz4815. PMID: 32671208
Self-renewal and differentiation of hematopoietic stem cells (HSCs) are orchestrated by the combinatorial action of transcription factors and epigenetic regulators. Here, we have explored the mechanism by which histone H4...
3.
Sheikh B, Guhathakurta S, Tsang T, Schwabenland M, Renschler G, Herquel B, et al.
Nat Cell Biol . 2020 Jun; 22(7):828-841. PMID: 32541879
Mutations in chromatin-modifying complexes and metabolic enzymes commonly underlie complex human developmental syndromes affecting multiple organs. A major challenge is to determine how disease-causing genetic lesions cause deregulation of homeostasis...
4.
Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska E, Peyronnet R, et al.
Nat Cell Biol . 2019 Oct; 21(10):1248-1260. PMID: 31576060
While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine acetyltransferase...
5.
Herquel B, Keime C, Davidson I
J Hepatol . 2015 Feb; 63(1):276-7. PMID: 25701693
No abstract available.
6.
Herquel B, Ouararhni K, Martianov I, Le Gras S, Ye T, Keime C, et al.
Nat Struct Mol Biol . 2013 Feb; 20(3):339-46. PMID: 23377542
Trim24 (Tif1α) and Trim33 (Tif1γ) interact to form a co-repressor complex that suppresses murine hepatocellular carcinoma. Here we show that Trim24 and Trim33 cooperatively repress retinoic acid receptor-dependent activity of...
7.
Herquel B, Ouararhni K, Davidson I
Transcription . 2012 Jan; 2(5):231-6. PMID: 22231120
TRIM24 (TIF1α), TRIM28 (TIF1β) and TRIM33 (TIF1γ) are related cofactors defining a subgroup of the tripartite motif (TRIM) superfamily comprising an N-terminal RING finger E3 ligase and a C-terminal PHD-Bromodomain...
8.
Herquel B, Ouararhni K, Khetchoumian K, Ignat M, Teletin M, Mark M, et al.
Proc Natl Acad Sci U S A . 2011 May; 108(20):8212-7. PMID: 21531907
TRIM24 (TIF1α), TRIM28 (TIF1β), and TRIM33 (TIF1γ) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors. TRIM24 interacts with the liganded retinoic acid...
9.
Khetchoumian K, Teletin M, Tisserand J, Herquel B, Ouararhni K, Losson R
Cell Cycle . 2008 Nov; 7(23):3647-52. PMID: 19029830
Retinoic acid (RA), the active derivative of vitamin A, is an important signaling molecule that controls various developmental processes and influence the proliferation and differentiation of a variety of cell...
10.
Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M, et al.
Nat Genet . 2007 Nov; 39(12):1500-6. PMID: 18026104
Hepatocellular carcinoma (HCC) is a major cause of death worldwide. Here, we provide evidence that the ligand-dependent nuclear receptor co-regulator Trim24 (also known as Tif1alpha) functions in mice as a...