Benjamin Heng
Overview
Explore the profile of Benjamin Heng including associated specialties, affiliations and a list of published articles.
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58
Citations
776
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Recent Articles
1.
Gunasegaran B, Krishnamurthy S, Chow S, Villanueva M, Guller A, Ahn S, et al.
Immunology
. 2025 Feb;
PMID: 39961658
Microglia are the primary resident immune cells of the central nervous system (CNS) that respond to injury and infections. Being critical to CNS homeostasis, microglia also have been shown to...
2.
Staats Pires A, Krishnamurthy S, Sharma S, Chow S, Klistorner S, Guillemin G, et al.
Neurol Neuroimmunol Neuroinflamm
. 2025 Jan;
12(2):e200372.
PMID: 39823555
Background And Objectives: Despite the absence of acute lesion activity in multiple sclerosis (MS), chronic neurodegeneration continues to progress, and a potential underlying mechanism could be the kynurenine pathway (KP)....
3.
Zeng G, Krishnamurthy S, Staats Pires A, Guller A, Chaganti J, Tun N, et al.
Hepatol Commun
. 2025 Jan;
8(12.
PMID: 39774873
Background: HE is a neuropsychiatric complication of liver disease characterized by systemic elevation in ammonia and proinflammatory cytokines. These neurotoxins cross the blood-brain barrier and cause neuroinflammation, which can activate...
4.
Mohamedali A, Heng B, Amirkhani A, Krishnamurthy S, Cantor D, Lee P, et al.
Cancers (Basel)
. 2025 Jan;
16(24.
PMID: 39766158
Background: Recent advancements in understanding plasma extracellular vesicles (EVs) and their role in disease biology have provided additional unique insights into the study of Colorectal Cancer (CRC). Methods: This study...
5.
Girithar H, Krishnamurthy S, Carroll L, Guller A, Bilgin A, Gluch L, et al.
Br J Cancer
. 2024 Nov;
131(12):1881-1892.
PMID: 39558063
Introduction: Metastasis remains the major cause of death in breast cancer (BrCa) and lacks specific treatment strategies. The kynurenine pathway (KP) has been suggested as a key mechanism facilitating progression...
6.
Gunasegaran B, Ashley C, Marsh-Wakefield F, Guillemin G, Heng B
BJC Rep
. 2024 Nov;
2(1):33.
PMID: 39516641
Background: Glioblastoma (GB) is a lethal and aggressive brain tumour. While molecular characteristics of GB is studied extensively, the aetiology of GB remains uncertain. The interest in exploring viruses as...
7.
Alnakli A, Mohamedali A, Heng B, Chan C, Shin J, Solomon M, et al.
BJC Rep
. 2024 Nov;
2(1):13.
PMID: 39516345
Colorectal cancer (CRC) poses a significant threat to many human lives worldwide and survival following resection is predominantly stage dependent. For early-stage cancer, patients are not routinely advised to undergo...
8.
Sharmin T, Chatterjee P, Doecke J, Ashton N, Huynh K, Pedrini S, et al.
J Neurochem
. 2024 Oct;
169(2).
PMID: 39473263
Alzheimer's disease (AD) pathogenesis involves dysregulation in diverse biochemical processes. Nevertheless, plasma tau phosphorylated at threonine 181 (P-tau181), a recognised AD biomarker, has been described to reflect early-stage cortical amyloid-β...
9.
Malepathirana T, Senanayake D, Gautam V, Engel M, Balez R, Lovelace M, et al.
Sci Rep
. 2024 Jun;
14(1):13558.
PMID: 38866809
Longitudinal studies that continuously generate data enable the capture of temporal variations in experimentally observed parameters, facilitating the interpretation of results in a time-aware manner. We propose IL-VIS (incrementally learned...
10.
Dehhaghi M, Heydari M, Kazemi Shariat Panahi H, Lewin S, Heng B, Brew B, et al.
Infection
. 2024 May;
52(5):2043-2059.
PMID: 38802702
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that may lead to various neurological and...