Benjamin Hackl
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Explore the profile of Benjamin Hackl including associated specialties, affiliations and a list of published articles.
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11
Citations
13
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Recent Articles
1.
Marksteiner J, Dostal C, Ebner J, Szabo P, Podesser B, Baydar S, et al.
Sci Rep
. 2025 Mar;
15(1):8991.
PMID: 40089543
Duchenne muscular dystrophy (DMD), a severe muscle disease caused by mutations in the gene encoding for the intracellular protein dystrophin, is associated with impaired cardiac function and arrhythmias. A causative...
2.
Lilliu E, Hackl B, Zabrodska E, Gewessler S, Karge T, Marksteiner J, et al.
Channels (Austin)
. 2024 Jun;
18(1):2361416.
PMID: 38836323
Alterations in ion channel expression and function known as "electrical remodeling" contribute to the development of hypertrophy and to the emergence of arrhythmias and sudden cardiac death. However, comparing current...
3.
Hong Y, Sourander C, Hackl B, Patton J, John J, Paatero I, et al.
Sci Rep
. 2024 May;
14(1):11174.
PMID: 38750129
Current treatments for anxiety and depression show limited efficacy in many patients, indicating the need for further research into the underlying mechanisms. JNK1 has been shown to regulate anxiety- and...
4.
Sauer J, Marksteiner J, Lilliu E, Hackl B, Todt H, Kubista H, et al.
Am J Physiol Heart Circ Physiol
. 2023 Dec;
326(2):H418-H425.
PMID: 38099845
Cardiac arrhythmias significantly contribute to mortality in Duchenne muscular dystrophy (DMD), a severe muscle illness caused by mutations in the gene encoding for the intracellular protein dystrophin. A major source...
5.
Hackl B, Zabrodska E, Gewessler S, Lilliu E, Putz E, Kiss A, et al.
Front Cardiovasc Med
. 2023 Oct;
10:1242763.
PMID: 37795481
Introduction: Transverse-aortic constriction (TAC) operation is a widely used animal model to induce hypertrophy and heart failure through left-ventricular pressure overload. In mice, the cardiac response to TAC exhibits considerable...
6.
Szabo P, Marksteiner J, Ebner J, Dostal C, Podesser B, Sauer J, et al.
Physiol Rep
. 2023 Apr;
11(7):e15664.
PMID: 37032434
The muscular dystrophies caused by dystrophin deficiency, the so-called dystrophinopathies, are associated with impaired cardiac contractility and arrhythmias, which considerably contribute to disease morbidity and mortality. Impaired Ca handling in...
7.
Berger V, Gabriel L, Lilliu E, Hackl B, Marksteiner J, Hilber K, et al.
Eur J Pharmacol
. 2023 Jan;
941:175495.
PMID: 36621601
Alterations in cardiac impulse conduction may exert both beneficial and detrimental effects. The assessment of ventricular conduction properties is of paramount importance both in clinical and in experimental settings. Currently...
8.
Marksteiner J, Ebner J, Salzer I, Lilliu E, Hackl B, Todt H, et al.
Membranes (Basel)
. 2022 Jun;
12(6).
PMID: 35736273
T-type Ca channels are strongly expressed and important in the developing heart. In the adult heart, these channels play a significant role in pacemaker tissues, but there is uncertainty about...
9.
Hackl B, Lukacs P, Ebner J, Pesti K, Haechl N, Foldi M, et al.
Front Pharmacol
. 2022 May;
13:809802.
PMID: 35586063
Ivabradine is clinically administered to lower the heart rate, proposedly by inhibiting hyperpolarization-activated cyclic nucleotide-gated cation channels in the sinoatrial node. Recent evidence suggests that voltage-gated sodium channels (VGSC) are...
10.
Hackl B, Todt H, Kubista H, Hilber K, Koenig X
Int J Neuropsychopharmacol
. 2021 Dec;
25(4):280-282.
PMID: 34871422
Psilocybin, a hallucinogen contained in "magic" mushrooms, holds great promise for the treatment of various psychiatric disorders, and early clinical trials are encouraging. Adverse cardiac events after intake of high...