Benjamin H Singer
Overview
Explore the profile of Benjamin H Singer including associated specialties, affiliations and a list of published articles.
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38
Citations
872
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Recent Articles
1.
Bongers K, Chanderraj R, Deng H, Song Y, Newstead M, Metcalf J, et al.
Shock
. 2024 Jun;
62(2):275-285.
PMID: 38888452
Sepsis is a common, heterogeneous, and frequently lethal condition of organ dysfunction and immune dysregulation due to infection. The causes of its heterogeneity, including the contribution of the pathogen, remain...
2.
Hill A, Khalil H, Laborc K, Kounelis-Wuillaume S, Gavade S, Johnston C, et al.
Biol Psychiatry Glob Open Sci
. 2024 Feb;
4(1):336-345.
PMID: 38298779
Background: Millions of sepsis survivors annually face neuropsychiatric sequelae of their illness. Corticosteroids are frequently administered for sepsis, and their use improves neuropsychiatric outcomes, but the mechanisms are unknown. In...
3.
Kumar A, Parthasarathy C, Prescott H, Denstaedt S, Newstead M, Bridges D, et al.
Hepatol Commun
. 2023 Aug;
7(9).
PMID: 37556193
Background: As critical care practice evolves, the sepsis survivor population continues to expand, often with lingering inflammation in many organs, including the liver. Given the concurrently increasing population of patients...
4.
Stephens A, Song Y, McClellan B, Su S, Xu S, Chen K, et al.
Biosens Bioelectron
. 2023 Jul;
237:115536.
PMID: 37473549
The search for reliable protein biomarker candidates is critical for early disease detection and treatment. However, current immunoassay technologies are failing to meet increasing demands for sensitivity and multiplexing. Here,...
5.
Su S, Song Y, Stephens A, Situ M, McCloskey M, McGrath J, et al.
Biosens Bioelectron
. 2023 Jan;
224():115030.
PMID: 36603283
Organ-on-a-chip platforms have potential to offer more cost-effective, ethical, and human-resembling models than animal models for disease study and drug discovery. Particularly, the Blood-Brain-Barrier-on-a-chip (BBB-oC) has emerged as a promising...
6.
Kumar A, Hjelmaas A, Singer B
Respir Med Case Rep
. 2022 Nov;
40:101755.
PMID: 36353064
There is a growing population of patients who require chronic noninvasive ventilation. While these patients often have no parenchymal lung disease, the use of positive pressure ventilation itself predisposes to...
7.
McCloskey M, Kasap P, Ahmad S, Su S, Chen K, Mansouri M, et al.
Adv Healthc Mater
. 2022 Jul;
11(18):e2200804.
PMID: 35899801
Advanced in vitro tissue chip models can reduce and replace animal experimentation and may eventually support "on-chip" clinical trials. To realize this potential, however, tissue chip platforms must be both...
8.
Gao Z, Song Y, Hsiao T, He J, Wang C, Shen J, et al.
ACS Nano
. 2021 Oct;
15(11):18023-18036.
PMID: 34714639
Cytokine storm, known as an exaggerated hyperactive immune response characterized by elevated release of cytokines, has been described as a feature associated with life-threatening complications in COVID-19 patients. A critical...
9.
Su S, Song Y, Newstead M, Cai T, Wu M, Stephens A, et al.
Small
. 2021 Jun;
17(31):e2101743.
PMID: 34170616
Integrated microfluidic cellular phenotyping platforms provide a promising means of studying a variety of inflammatory diseases mediated by cell-secreted cytokines. However, immunosensors integrated in previous microfluidic platforms lack the sensitivity...
10.
Denstaedt S, Bustamante A, Newstead M, Moore B, Standiford T, Zemans R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 Jun;
321(2):L451-L465.
PMID: 34161747
Millions of people who survive sepsis each year are rehospitalized and die due to late pulmonary complications. To prevent and treat these complications, biomarkers and molecular mediators must be identified....